DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and HXT15

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_010036.1	Gene:	HXT15 / 851352	SGDID:	S000002404	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	513	Identity:	121/513 - (23%)
Similarity:	202/513 - (39%)	Gaps:	126/513 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCLPKRVGG--PAIQSVATALGNILCFNFGLMFGITPAHMT--LYESEERTPLNQATDPAGTAWL 61
            :|.|...||  |...|..|| |.|...||.:.|| :..|.|  .|.|..|..|..|....|.: :
Yeast    63 LCYPVSFGGFLPGWDSGITA-GFINMDNFKMNFG-SYKHSTGEYYLSNVRMGLLVAMFSVGCS-I 124

  Fly    62 TGYLF--LSAALG---ALVSGFLALKIGPKSVLLCSGLLQISG---WACIHFGYDIVHIYASRLF 118
            .|..|  |:..||   |:|...|...:|        .::|||.   |    :.|     :..::.
Yeast   125 GGVAFARLADTLGRRLAIVIVVLVYMVG--------AIIQISSNHKW----YQY-----FVGKII 172

  Fly   119 AGVASGAAFVVLPIFINEIAESREKAARLTFTIELWRTLGILIGFV-----------------LG 166
            .|:.:|...|:.|:.::|||.: :....|....:|..|.||.:|:.                 :|
Yeast   173 YGLGAGGCSVLCPMLLSEIAPT-DLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVG 236

  Fly   167 FYVPYAFVNIVGCAVSFVFTMTFPFVQESPHYYL----RKNNMASLEKSLRWYRGIRDIDDREKP 227
            ....:|.:.|||..:          |.|||.|.:    .:....|:.|       |..:.. |.|
Yeast   237 LCFLWALIIIVGMLL----------VPESPRYLIECERHEEACVSIAK-------INKVSP-EDP 283

  Fly   228 EYLSELNEFHAELRSRDKNVGSTPMSHGYIIRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTG- 291
            ..|.:.:|.:|.:.:: :.:|.......:.::...:..|:|      |:.|:     .||..||
Yeast   284 WVLKQADEINAGVLAQ-RELGEASWKELFSVKTKVLQRLIT------GILVQ-----TFLQLTGE 336

  Fly   292 -----YST------------ETNYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIA- 338
                 |.|            ||: :||.:......::|.:|..::.|:  .||  ||.||:::|
Yeast   337 NYFFFYGTTIFKSVGLTDGFETS-IVLGTVNFFSTIIAVMVVDKIGRR--KCL--LFGAASMMAC 396

  Fly   339 LALFKAYGHLWLLGNWADRYLP---------IILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDL 394
            :.:|.:.|...|..:..|.  |         |:.....:...:....|:|.:|.:|..|:|:...
Yeast   397 MVIFASIGVKCLYPHGQDG--PSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSK 459

  Fly   395 LYSLASAVSWL--LLFGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISLPLLPET 450
            ..|:::|.:||  .|.|....|  :..:|.   ..|.:||.|..:.:.|.....||||
Yeast   460 AMSISTAFNWLWQFLIGFFTPF--ITGSIH---FYYGYVFVGCLVAMFLYVFFFLPET 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	33/162 (20%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	99/452 (22%)
HXT15	NP_010036.1	MFS_HXT	62..524	CDD:340914	121/513 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342363
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740