DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and INT4

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001328028.1	Gene:	INT4 / 827346	AraportID:	AT4G16480	Length:	582	Species:	Arabidopsis thaliana

Alignment Length:	565	Identity:	112/565 - (19%)
Similarity:	214/565 - (37%)	Gaps:	145/565 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYL----FLSAALGAL 74
            :::..:|.:|   ||...|:....: |:..|:...:::.|      ||...:    ...|.:||.
plant    31 ALSAGIGGLL---FGYDTGVISGAL-LFIKEDFDEVDKKT------WLQSTIVSMAVAGAIVGAA 85

  Fly    75 VSGFLALKIGPKSVLLCSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEIAE 139
            |.|::..|.|.:..:|.:.:|.:.|...:.|......|...|:|.|...|.|.:..|::|:|.:.
plant    86 VGGWINDKFGRRMSILIADVLFLIGAIVMAFAPAPWVIIVGRIFVGFGVGMASMTSPLYISEASP 150

  Fly   140 SREKAARLTFTIELWRTLGILI--GFVLGFYVPYAFVNIVG------------CAVSFVFTMTFP 190
            :|.:.|       |..|.|:||  |....:.:..|||:..|            ..|.||..::.|
plant   151 ARIRGA-------LVSTNGLLITGGQFFSYLINLAFVHTPGTWRWMLGVAGVPAIVQFVLMLSLP 208

  Fly   191 FVQESPHYYLRKNNMASLEKSLRWYRGIRDID----------DREKPEYLSELNEFHAELRSRDK 245
               |||.:..||:.:|.....|.......:::          :.||.:.....:.|.|:|:..
plant   209 ---ESPRWLYRKDRIAESRAILERIYPADEVEAEMEALKLSVEAEKADEAIIGDSFSAKLKGA-- 268

  Fly   246 NVGSTPMSHGYIIRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTETNYVVL----ASAQC 306
             .|:..:..|....:|     :.|..:..|:...:.|:...:...||::....:.|    :....
plant   269 -FGNPVVRRGLAAGIT-----VQVAQQFVGINTVMYYSPSIVQFAGYASNKTAMALSLITSGLNA 327

  Fly   307 AGALLARLVGPRLPRK------------LLLCLSSLFAAAAVIA-------------LALFKAYG 346
            .|::::.:...|..|:            .|:.|:::|:.||:.|             .|...||.
plant   328 LGSIVSMMFVDRYGRRKLMIISMFGIIACLIILATVFSQAAIHAPKIDAFESRTFAPNATCSAYA 392

  Fly   347 HL---------W-------------------------------LLGNWADR-------------- 357
            .|         |                               :....:.|
plant   393 PLAAENAPPSRWNCMKCLRSECGFCASGVQPYAPGACVVLSDDMKATCSSRGRTFFKDGCPSKFG 457

  Fly   358 YLPIILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLFGMIEAFNAVKATIA 422
            :|.|:.|.:.:.:.:.|:..:..:|:||:.|.:...|...:|:..:|:....:.|:|  :..|.|
plant   458 FLAIVFLGLYIVVYAPGMGTVPWIVNSEIYPLRYRGLGGGIAAVSNWVSNLIVSESF--LSLTHA 520

  Fly   423 PGLLLYLWVFAGASIFVGLISLPLL-PETRNRRPSAVQR--ELGY 464
            .|......:|||.|. :||..:.|| |||:..:...|::  |:|:
plant   521 LGSSGTFLLFAGFST-IGLFFIWLLVPETKGLQFEEVEKLLEVGF 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	38/155 (25%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	101/506 (20%)
INT4	NP_001328028.1	MFS_HMIT_like	33..547	CDD:340918	106/544 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900