Protein Alignment CG8837 and SLC2A2

DIOPT Version :9

• Sequence 1: NP_001285582.1
• Gene: CG8837 / 33545
• FlyBaseID: FBgn0031520
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 113/520 - (21%)
• Similarity: 197/520 - (37%)
• Gaps: 106/520 - (20%)

  Fly     6 RVGGPAIQSVATA-LGNILCFNFGLMFGITPA----------HMTLYESEERTPLN----QATD- 54
            :|.|..:.:|.|| ||:   |.||...|:..|          |:.....::|..:|    .:||
Human     5 KVTGTLVFTVITAVLGS---FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTDE 66

  Fly    55 ---------PAGTAW--------------LTGYLFLSAALGALVS----GFLALKIGPKSVLLCS 92
                     |..|.|              |......|.|:|.:.:    |:|...:|....:|.:
Human    67 LPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVA 131

  Fly    93 GLLQISGWACIHF---GYDIVHIYASRLFAGVASGAAFVVLPIFINEIAESREKAARLTFTIELW 154
            .:|.:.|...:.|   |...:.|.|.|..:|:..|....::|::|.|||.:..:.|..||. :|.
Human   132 NILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFH-QLA 195

  Fly   155 RTLGILIG------FVLGFY-VPYAFVNIVGCAVSFVFTMTFPFVQESPHY-YLRKNNMASLEKS 211
            ...||||.      |:||.| :.:..:.:.|........:.| |..|||.| |::.:.....::|
Human   196 IVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLF-FCPESPRYLYIKLDEEVKAKQS 259

  Fly   212 LRWYRGIRDIDDREKPEYLSELNEFHAELRSRDKNVGSTPMSHGYIIRL---------TFVSFLL 267
            |:..||..|:        ..::||...|   |::......:|   ||:|         ..|:.:|
Human   260 LKRLRGYDDV--------TKDINEMRKE---REEASSEQKVS---IIQLFTNSSYRQPILVALML 310

  Fly   268 TVCAKLSGVFVELNYAADFLGRTG-----YST----ETNYVVLASAQCAGALLARLVGPRLPRKL 323
            .|..:.||:.....|:.......|     |:|    ..|.|..|    ....|....|.|  ...
Human   311 HVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTA----VSVFLVEKAGRR--SLF 369

  Fly   324 LLCLSSLFAAAAVIALALFKAYGHLWLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSEVLP 388
            |:.:|.:|..|..:::.|.......|:      .|:.:|.:.:.::....|..|:...:.:|...
Human   370 LIGMSGMFVCAIFMSVGLVLLNKFSWM------SYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFS 428

  Fly   389 TKLHDLLYSLASAVSWLLLFGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISLPLLPETRNR 453
            ........::|:..:|...|.:...|..:.....|   ...::|||..:...|.:...:|||:.:
Human   429 QGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGP---YVFFLFAGVLLAFTLFTFFKVPETKGK 490

  Fly   454  453
            Human   491  490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	40/175 (23%)
		Sugar_tr	58..453	CDD:278511	95/441 (22%)
SLC2A2	NP_000331.1	Sugar_tr	14..499	CDD:278511	111/511 (22%)
		MFS	98..485	CDD:119392	89/417 (21%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	314..320		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144025
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840