DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and slc2a13b

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_005163236.1	Gene:	slc2a13b / 559440	ZFINID:	ZDB-GENE-090812-1	Length:	641	Species:	Danio rerio

Alignment Length:	545	Identity:	115/545 - (21%)
Similarity:	195/545 - (35%)	Gaps:	130/545 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 TALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAW---LTGYLFLSAALGALVSGF 78
            :|||..|   ||...|:....|.|.:.|::         ..:.|   |......:||:.||..||
Zfish    42 SALGGFL---FGYDTGVVSGAMLLLKREKK---------LSSVWQELLVSITVGAAAVSALAGGF 94

  Fly    79 LALKIGPKSVLLCSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEIAESREK 143
            |..:.|.:..:|.:..:..:|...:....:...:...||..|:..|.|.:.:|::|.|::.. :.
Zfish    95 LNGRFGRRVCILLASFIFCAGGIILSVARNKEALLCGRLTVGLGLGIASMTVPVYIAEVSPP-DL 158

  Fly   144 AARLTFTIELWRTLGILIGFVLG---FYVPY------AFVNIVGCAVSFVFTMTFPFVQESPHYY 199
            ..:|.....|:.|.|..|..|:.   .|:|:      ..:::|..|:.|   :.|.|:.|||.:.
Zfish   159 RGQLVTVNTLFITGGQFIASVVDGAFSYLPHDGWRFMLGLSVVPAALQF---LGFLFLPESPRWL 220

  Fly   200 LRKNNMASLEKSLRWYRGIRDIDDREKPEYLSELNEFHAELRSRDKNVGSTPMSHGYII-----R 259
            |:|....:....||..||  |:|..|      |.......::...::|...|:....:.     |
Zfish   221 LQKGFTQNALLVLRQIRG--DVDVEE------EFESIRCSIQEEQRDVAGGPVLWRMLASPPARR 277

  Fly   260 LTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTETNYVVLASAQCAGALLARLVG----PRLP 320
            ...|...|.:..:|:|:...:.|:|..|..:|...:...:.||:.......|..|||    .|:.
Zfish   278 ALIVGCGLQMFQQLAGINTVMYYSATILQMSGVQDDQMAIWLAAGTAFTNFLFTLVGVWLVERVG 342

  Fly   321 RKLLLCLSSLFAAAAVIALA---LFKAYG-------------HLWLLGN---------------- 353
            |:.|...|.|..|.:::.||   |..|..             |....||
Zfish   343 RRRLTMASLLGTAVSLMVLAAGFLLSAQASPPVTFHPSNPSIHNSTCGNYGFCESCMLDPDCGFC 407

  Fly   354 ----------------------------------------WADRYLP-----IILLAIQLALVSF 373
                                                    ||..|.|     ::||.:.|.|..|
Zfish   408 YGLNATAVVQSSCVPVDPANTETAALGRCFNGTQKASSVFWAYNYCPTPYSWVVLLGLILYLAFF 472

  Fly   374 --GLYPLAAVVSSEVLPTKLHDLLYSLASAVSWL--LLFGMIEAFNAVKATIAPGLLLYLWVFAG 434
              |:.|:...|:||:.|........:.::.|:|:  :|..:.....|...|......||..:...
Zfish   473 APGMGPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAQYLTYYGAFFLYAALALL 537

  Fly   435 ASIFVGLISLPLLPETRNRRPSAVQ 459
            ..:||.    ..||||:..|...::
Zfish   538 GFVFVS----GCLPETKGLRLEEIE 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	32/149 (21%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	104/496 (21%)
slc2a13b	XP_005163236.1	Sugar_tr	38..561	CDD:278511	115/545 (21%)
slc2a13b	XP_005163236.1	MFS	40..542	CDD:119392	108/523 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576920
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840