DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001178480.1	Gene:	Slc2a9 / 501925	RGDID:	1597012	Length:	545	Species:	Rattus norvegicus

Alignment Length:	498	Identity:	119/498 - (23%)
Similarity:	197/498 - (39%)	Gaps:	72/498 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PKRVGGPAIQSVATALGNILCFNFGLMFGI--------TPAHMTLYESEERTPLNQATDPAGTAW 60
            |:|....:...:..||  :..|....::|.        ||.....|.........|..||.....
  Rat    34 PRRTKNWSCSLIVAAL--VGAFGSSFLYGYNLSVVNAPTPYIKAFYNETWYRRHGQPIDPDTLTL 96

  Fly    61 LTGYLFLSAALGALVSGFLALK-----IGPKSVLLCSGLLQISG---WACIHFGYDIVHIYASRL 117
            |........|:|.|| |.|.:|     :|.|..||.:....||.   .||.........:...|.
  Rat    97 LWSVTVSIFAIGGLV-GTLMVKMIGKFLGRKYTLLVNNGFAISAALLMACSLQAGTFEMLIVGRF 160

  Fly   118 FAGVASGAAFVVLPIFINEIA--ESREKAARLTFTIELWRTLGILIGFVLGF--------YVPYA 172
            ..||..|.|...||:::|||:  |.|....::|   .::..:|:..|.:||.        ..||.
  Rat   161 IMGVDGGIALSALPMYLNEISPKEIRGSLGQVT---AIFICIGVFSGQLLGLPELLGKERTWPYL 222

  Fly   173 FVNIVGCAVSFVFTMTFPFVQESPHYYL-RKNNMASLEKSLRWYRGIRDIDDREKPEYLSELNEF 236
            |..|:..|::.:.::  ||:.|||.|.| .|::.|...|:.:.:.|..|:.        .||.|.
  Rat   223 FGVIIVPALAQLASL--PFLPESPRYLLFEKHDEAGATKAFQTFLGKADVS--------QELEEA 277

  Fly   237 HAELRSRDKN---VGSTPMSHGYIIRLTFVSFLLTVCA-KLSGVFVELNYAADFLGRTGY-STET 296
            .||.|.: :|   |....:.....:|...::.::|:.: :|.|:.....|.....|:.|. ..:.
  Rat   278 LAESRVQ-RNLRLVSVFELLRAPFVRWQVITVVITMASYQLCGLNAIWFYTNSIFGKAGVPQDKI 341

  Fly   297 NYVVLASA--QCAGALLARLVGPRLPRKLLLC----LSSLFAAAAVIALALFKAYGHLWLLGNWA 355
            .|:.|::.  :...|:.:.||..||.|:.||.    |.:||.....:.|.|.....  |:
  Rat   342 PYITLSTGGIETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGMLTVTLTLQDQAP--WI----- 399

  Fly   356 DRYLPIILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLF--GMIEAFNAVK 418
             .||.|:.:...:|....|...:..:::.|..........:.:|..|:||..|  |::..|
  Rat   400 -PYLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFIIAGTVNWLSNFVVGLLFPF---- 459

  Fly   419 ATIAPGLLLYLW-VFAGASIFVGLISLPLLPETRNRRPSAVQR 460
              |...|..|.: |||...|...:....:||||:||..:.:.:
  Rat   460 --IQKSLESYCFLVFATICIAGAIYFYFVLPETKNRTHAEISQ 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	41/155 (26%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	105/427 (25%)
Slc2a9	NP_001178480.1	Sugar_tr	47..502	CDD:278511	117/485 (24%)
Slc2a9	NP_001178480.1	MFS	49..486	CDD:119392	110/467 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337794
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840