DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and AgaP_AGAP008720

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_001237606.1	Gene:	AgaP_AGAP008720 / 4578076	VectorBaseID:	AGAP008720	Length:	215	Species:	Anopheles gambiae

Alignment Length:	184	Identity:	44/184 - (23%)
Similarity:	75/184 - (40%)	Gaps:	16/184 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IQSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYLFLSAALGALVS 76
            :|.|...:.||...:.|:  ||....:.:.|....|.....|:...| |......:....|.|:|
Mosquito    40 VQIVTAVVANITIISSGM--GIGFPSIAMIELTNSTTSVVLTESDAT-WFASITSIMCPFGGLLS 101

  Fly    77 GFLALKIGPKSVLLCSGLLQISGWACIHFGYD------IVHIYASRLFAGVASGAAFVVLPIFIN 135
            |:|..|:|.|..|....::.|..||.:.|...      .:.:..:|:..|:|.|.:.....::..
Mosquito   102 GYLLDKVGRKKTLYFINIISIVSWAIMSFASRTDSATLFIQLIVARIIIGIAIGLSSTPASVYAA 166

  Fly   136 EIAESREKAARLTFTIELWRTLGILIGFVLG--FYVPYAFVNIVGCAVSFVFTM 187
            |:|....: .|||........:|:|..:.||  |...:.||    |.:..:||:
Mosquito   167 EVAHPNLR-GRLTLLTAFCTAIGMLSIYTLGYVFKNDWRFV----CMICGIFTV 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	34/142 (24%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	34/138 (25%)
AgaP_AGAP008720	XP_001237606.1	MFS	46..>215	CDD:119392	41/176 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900