DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and sut2

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	509	Identity:	131/509 - (25%)
Similarity:	209/509 - (41%)	Gaps:	91/509 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PKRVGG--PAIQSV--ATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTA----- 59
            |.:|.|  |.:..:  ...||..:  ..|..||:..|...:.:...:..|....|...||
  Fly     9 PPKVNGWTPLLMLICLTVTLGTTI--PVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDI 71

  Fly    60 -W--LTGYLFLSAALGALVSGFLALKIGPKSVLLCSGLL-QISG----WACIHFGYDIVHIYASR 116
             |  :.....:....|:..|..|..|.|.|..|:.|.:| .:||    |.  .....:..:...|
  Fly    72 LWTSIVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWC--RAAKSLEMLMTGR 134

  Fly   117 LFAGVASGAAFVVLPIFINEIAESREKAARLTFTIELWRTLGILIGFVLGFYV------------ 169
            ...|:||...|...|:::.|.|.|     .|:.::.::..:|:..|.:|....
  Fly   135 FLGGIASALIFTAQPMYLLESAPS-----ELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLW 194

  Fly   170 PYA--FVNIVGCAVSFVFTMTFPFVQESPHY-YLRKNNMASLEKSLRWYRGIRDIDDREKPEYLS 231
            |||  |.:::..| |.|....||   |||.: ||.|.:.|:.||:|...|| |:.::    |...
  Fly   195 PYALSFYSLLVMA-SLVLLWWFP---ESPRWLYLHKRDSAASEKALLRLRG-RNTEE----EVHQ 250

  Fly   232 ELNEFHAELRSRDKNVGSTPMSHGYIIRLTFVSF-LLTVCA-----KLSGVFVELNYAADFLGRT 290
            ||.|..|.|.::..:..|:..|   ::|.:.:.. ||.||:     :|||:.....|:...|...
  Fly   251 ELLEMKATLEAKSSSEVSSLCS---VLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNA 312

  Fly   291 GYS----TETNYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALAL---FKAYGHL 348
            |:|    |..| :.:.|.....:||..|:..|.||:.|:.:|....|.|::|::|   |......
  Fly   313 GFSDGAATWLN-LGIGSFNLCTSLLGPLLIRRFPRRPLMMISCSMCALALLAMSLGLFFLERSES 376

  Fly   349 WLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWL--LLFGMI 411
            .:|..:...::...:|..||     ||.|:|..:.||:|......:..|:.|..||:  .|.||.
  Fly   377 TVLTYFCAAFILTFILGFQL-----GLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMC 436

  Fly   412 EAFNAVKATIAPGLLLYLW-VFA-----GASIFVGLISLPLLPETRNRRPSAVQ 459
            ..           ||..:| .||     ...|:..|::...|||||.|.|..|:
  Fly   437 FP-----------LLQSVWSSFAFIPCMCVCIYCLLLTWRYLPETRGREPKDVK 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	38/164 (23%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	116/443 (26%)
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	124/487 (25%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	108/425 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840