DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and CG14605

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_649707.3	Gene:	CG14605 / 40867	FlyBaseID:	FBgn0037486	Length:	432	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	112/459 - (24%)
Similarity:	194/459 - (42%)	Gaps:	69/459 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GLMFG-ITPAHMTLYESEERTPLNQATDPAGTAWL-----TGYLFLSAALGALVSGFLALKIGPK 86
            |:..| .:|...||.  .:.:|:....|.:...|:     .|.|..:..:...||.|     |.|
  Fly     6 GISLGWFSPTLPTLI--SDNSPIGHPIDISEVKWIGASFGIGCLICNMVICVPVSYF-----GIK 63

  Fly    87 SVLLCSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEIAESREKAARLTFTI 151
            ..:....|..|..|..|:|....::.|..|:..|::.|...|..|:||.|::::   :.|.|...
  Fly    64 KCMYFVPLPNILNWVLIYFASKSLYFYVCRVLLGISGGTLVVCFPVFIAEVSDN---SVRGTLGS 125

  Fly   152 ELWRTL--GILIGFVLGFYVPYAFVNIVGCAVSFV----FTMTFPFVQESPHYYLRKNNMASLEK 210
            ....||  ||.:||||.:.:.|   :::.|.|.|:    ..:..| :.|.|...|::.:....||
  Fly   126 FFMMTLCSGITVGFVLVYCLSY---HVLPCVVIFLPILYLCLIIP-LPEPPQDLLKRGHEEKAEK 186

  Fly   211 SLRWYRGIRDIDDREKPEYLSELNEFHAELRSRDKNVGSTPMSHGYIIRLTFVSFLLTVCAK--- 272
            |..:|:.:.. |..::.:..:|.::.      |:|.:.|     |...::|...|...|..|
  Fly   187 SFCFYKNLSK-DPAQQDDNKAEFDKL------RNKVLAS-----GIAEKITPADFFNKVSGKAFG 239

  Fly   273 ----------LSGVFVELNYAADFLGRTGYSTETNY--VVLASAQCAGALLARLVGPRLPRKLLL 325
                      :||.|...||::....:.|...|.|.  :.|...|..|.:.|.|:..|:.|:|||
  Fly   240 LIAVLLLSNQMSGSFAIFNYSSTIFEQLGSRMEPNLCGIFLGVVQIFGLISAVLLVDRVGRRLLL 304

  Fly   326 CLSSLFAAAAVIALALFKAYGHLWLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSEVLPTK 390
            ..|......|.:.:.|.|::.....|.|  :.::.:.|:.|.....|.|:..|..|:..|:||.|
  Fly   305 IPSLAGMGLAELGVGLLKSFASQDFLHN--NGWIALTLMGIVSFTASAGIVALTFVIIVELLPFK 367

  Fly   391 LHDLLYSLASAVSWLLLFGMIEAFNAVKATIAPGLL----LYLWVFAGASI-FVGLISLPL-LPE 449
            :.      |..:|..:....:..|.|:  ...|.|:    :::.:|..||. .:||:.|.: |||
  Fly   368 IR------APGISISMCGLSLSVFIAL--ITYPVLINDYGVHVTMFVSASFCLLGLVVLGIFLPE 424

  Fly   450 TRNR 453
            ||.:
  Fly   425 TRGK 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	38/148 (26%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	105/426 (25%)
CG14605	NP_649707.3	MFS	1..421	CDD:119392	107/450 (24%)
CG14605	NP_649707.3	MFS_1	1..387	CDD:284993	98/414 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444361
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004527
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740