DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and CG14606

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster

Alignment Length:	465	Identity:	126/465 - (27%)
Similarity:	225/465 - (48%)	Gaps:	45/465 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYLFLSAALGALVSG 77
            |.:||...:|:....|:..|.....:.|..|:| :||.........:|:...:.|.:..|.::.|
  Fly    19 QFIATMTVHIMTLTHGIAVGWLSPSLRLLASDE-SPLGDPLTITQASWVGSLIGLGSLTGNIIFG 82

  Fly    78 FLALKIGPKSVLLCSGLLQISG---WACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEIAE 139
            .|..::|.|   :|...|.|..   |..|:...|:.::||.|..||::.|..:|||||||.|||:
  Fly    83 LLLDRLGRK---VCMYFLAIPNMIYWILIYSAQDVTYLYAGRFLAGMSGGGCYVVLPIFIAEIAD 144

  Fly   140 SREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVGCAVSFVFTMTFPFVQESPHYYLRKNN 204
            :..:.| |:....::.::|:::||.|..|:||..:..:..|:..||.::...:.|:|.|.||:..
  Fly   145 NSVRGA-LSSMAMMYVSIGMMVGFTLASYLPYYLMPCIIVALPVVFMLSVIGLSETPQYLLRRGR 208

  Fly   205 MASLEKSLRWYRGIR--DIDDREKPEYLS---ELNEFHAELRSRDKNVGSTPMSHGY-------I 257
            ....|||..:|:.:.  ...|:|..::.:   |.:.|..::.|     |....|..:       .
  Fly   209 DDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLS-----GGVTESISWRDFINVPT 268

  Fly   258 IRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTE--TNYVVLASAQCAGALLARLVGPRLP 320
            :::..:.|:|.:|.:|||.|...||.:......|.:.:  |:.:|:.:||..|...|.::..||.
  Fly   269 LKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIFSAVVLVDRLG 333

  Fly   321 RKLLLCLSSLFAAAAVIALALFKAYGHLWLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSE 385
            |::||..|........:|:||.|.:.....|..  :.:||::::.:...:.|.|:..|..::..|
  Fly   334 RRVLLLTSMGGMGLGELAIALLKCFASDEFLNQ--NGWLPLVIMCLVACIASLGVIALIFIIIIE 396

  Fly   386 VLPTKLHDLLYSLASAVSWLLLFGMIEAFNAVKATIAP------GLLLYLWVFAGASIFVGLISL 444
            :||.|:.    |:.:::|.....|.|  |.|:|  |.|      ||...:::.||..:| |.|.|
  Fly   397 LLPAKIR----SIGTSLSMATFSGFI--FVALK--IYPTMIYDQGLAATMFMSAGMCLF-GFIVL 452

  Fly   445 PL-LPETRNR 453
            .| ||||:.:
  Fly   453 GLFLPETKGK 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	41/140 (29%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	115/418 (28%)
CG14606	NP_001334690.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444358
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004527
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740