DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and CG15406

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_608761.2	Gene:	CG15406 / 33542	FlyBaseID:	FBgn0031517	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	110/458 - (24%)
Similarity:	188/458 - (41%)	Gaps:	27/458 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYLFLSAALGALVSG 77
            |.:.:....::.|..|:..|.....:....|.:.|||:...|....:||...:.:....|.....
  Fly    18 QLLVSLSATLITFCHGIALGWLSPMLPKLLSPQETPLSFYIDVNEASWLGAVISIGGISGNFSFS 82

  Fly    78 FLALKIGPKSVLLCSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEIAESRE 142
            :|..:.|.|..:....:.....|...:|...|..:|.:|:|||:..|..||||||||.|||::..
  Fly    83 YLMNRFGRKVSIYALAVPHTCIWFLFYFAQSIEWLYVARVFAGLTGGGMFVVLPIFIGEIADNSI 147

  Fly   143 KAARLTFTIELWRTLGILIGFVLGFYVPYAFV--NIVGCAVSFVFTMT-FPFVQESPHYYLRKNN 204
            : .||.....|....||::|||:..::.|..:  .:||..|.:|...| :|   |.|...:|...
  Fly   148 R-GRLCSFFTLTMNTGIMVGFVVSSHIAYHVIPCAVVGLPVLYVLLATRYP---EPPQQLIRWKR 208

  Fly   205 MASLEKSLRWYRGI--RDIDDREKPEYLSELNEFHAELRSRDKNVGSTPMSHGYI-----IRLTF 262
            ....|||||:||..  .::...|:..|....:|....::.::.:.....:|....     ::...
  Fly   209 EEEAEKSLRYYRRCDGPNVSKEEERAYQKHFDEMRLAIQQQNNDTDDNGLSMSDFLTKRSLKALA 273

  Fly   263 VSFLLTVCAKLSGVFVELNYAADFLG--RTGYSTETNYVVLASAQCAGALLARLVGPRLPRKLLL 325
            ...:|.|....:|.|...||.::...  .|.....||.:::.:.|..|.|.:..:..|..||:||
  Fly   274 TGLVLMVANIFTGTFAFNNYMSNIFDAVHTQLDPNTNTIIIGAVQILGTLASIYLVDRYGRKILL 338

  Fly   326 CLSSLFAAAAVIALALFKAYGH-----LWLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSE 385
            .:|...:.....|..|:..|..     |.....|    ||:.|:|..:.:.:.|:..:..||..|
  Fly   339 IVSCAGSGIGTSAFGLYAFYAEEQKVDLSAFSAW----LPVTLMAFIIFIANVGVISVTMVVLVE 399

  Fly   386 VLPTKLHDLLYSLASAVSWLLLFGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISLPLLPET 450
            :||.|:..:..|..........|..::.|..:...:  ||...:|..|..|:......:..|.||
  Fly   400 ILPQKIRAVATSFCLGCLSFFAFASLKTFPLMMFHL--GLAATMWFCAAVSVICLFYVVVCLEET 462

  Fly   451 RNR 453
            :.|
  Fly   463 KGR 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	42/140 (30%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	100/411 (24%)
CG15406	NP_608761.2	MFS	23..458	CDD:119392	105/444 (24%)
CG15406	NP_608761.2	SP	26..466	CDD:273317	109/450 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444359
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004527
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740