DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and CG32054

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_729588.1	Gene:	CG32054 / 326185	FlyBaseID:	FBgn0052054	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	486	Identity:	97/486 - (19%)
Similarity:	168/486 - (34%)	Gaps:	132/486 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SEERTPLNQATDPAG---------TAWLTGY---------------LFLSAALGALVSGFLALKI 83
            :::..|.:.|...||         .||..|:               .|:...:||::|.||...:
  Fly   114 NQKNKPQSNAVGAAGLIFVSGGMNIAWSIGFRGVLHYKTTEHNFAAWFIGGIIGAVISWFLINNV 178

  Fly    84 GPKSVLLCSGLLQI-----------SGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEI 137
            ..|.||:.|..|.:           ||.|.:          |:....|:|:|..|........|:
  Fly   179 AKKYVLIFSSFLVMIGGILTTSTKNSGDATL----------AASYLDGIANGLVFAPFMALAGEV 233

  Fly   138 AESREKAARLTFTIELWRTLGILIGFV---------LGFYVPYAFVNIVGCAVSFVFTMTFPFVQ 193
            :.|..:........::...|||.:..:         ...|..::..|:.|     |.::.:.|:.
  Fly   234 SVSYMRGMVSASIEQMCFGLGIFLQIIYTSTWNSTAYPSYNSFSAENMKG-----VLSIIYGFLA 293

  Fly   194 ---------ESPHYYLRKNN-----MASLEKSLRWYRGIRDIDDR--EKPEYLSELNEFHAELRS 242
                     |||...|.|||     :.:|.:..|.|....:..::  |..:||::..|.     |
  Fly   294 LIIGSLLCIESPVIMLAKNNDEQGAIDALRRLQRPYTLTNETFEQLAEHKKYLAQNKEL-----S 353

  Fly   243 RDKNVGSTPMSHGYIIRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTET----------- 296
            ..:::|....:   .|||.   ||..:.|.....||.:.:...|....||.:.:
  Fly   354 MGQSIGQALPT---FIRLV---FLRGLNAMSISKFVMIGFVYSFASPYGYVSPSVGWFIGFGVCR 412

  Fly   297 ---NYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALALFKAYGHLWLLGNWADRY 358
               |::.....:..|.....|:|      |::|....|..|....:..:..       ||
  Fly   413 WMGNFIATFCMESCGRKKPTLLG------LIVCSVMSFVVAGQFNIFTYNT-------GN----- 459

  Fly   359 LPIILLAIQL-ALVSFGLYPLAAVVSSEVLP--TKLHDLLYSLASAVSWLLLFGMIEAFNAVKAT 420
             .|:||..:| |.::|   ...:...||..|  .|.|.:.::....:...|:..:|...::..|.
  Fly   460 -NIMLLVFELFAGIAF---TATSPYLSEAFPLEVKQHFISFTFIGEMLVFLVLTLIRWSSSGGAN 520

  Fly   421 IAPGLLLYLWVFAGASIFVGLISLPLLPETR 451
                   |.:|..|..:|.....|..|||||
  Fly   521 -------YFYVMGGLYLFGFFFGLVCLPETR 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	33/181 (18%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	93/462 (20%)
CG32054	NP_729588.1	Pro-rich	<7..101	CDD:291893
CG32054	NP_729588.1	MFS	157..539	CDD:119392	85/436 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444373
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740