DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and CG33281

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	129/483 - (26%)
Similarity:	212/483 - (43%)	Gaps:	48/483 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GGPAIQSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQA-TDPAGTAWLTGYLFLSAAL 71
            ||...|.:|....||:..::|...| .|:...|..|.|.:||:.. ..|....|:...:.|...:
  Fly     5 GGDKYQYLAAISVNIISISYGAFCG-WPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLV 68

  Fly    72 GALVSGFLALKIGPKSVLLCSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINE 136
            |..:..:||.:||.|..|:...|..:.||..|.|....:|:..:|...|.|.|..|.|:||:|.|
  Fly    69 GTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAE 133

  Fly   137 IAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVGCAVSFVFTMTFPFVQESPHYYLR 201
            :|....:.....|.: |....|:::.||||:|..||.|:.:..::||||...|.|:.|:|.:..:
  Fly   134 LASDNIRGILGVFLV-LTCNFGLVLAFVLGYYFNYAQVSWIVSSLSFVFVGCFWFMPETPQHLAK 197

  Fly   202 KNNMASLEKSLRWYRGIRDIDDREKPEYLS-ELNEFHAELRSRDKNVGSTPMSHG---------- 255
            .|.:...|.|||:||.|:....:|..|.|. ||.:.....::....|.....:.|
  Fly   198 INKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGK 262

  Fly   256 ----YIIRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTETNY--VVLASAQCAGALLARL 314
                ::|.|..:||     .:|.|.|..|||.|....:.|.|.....  :::...|..|...:.:
  Fly   263 TRKAFLIGLGLISF-----NQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTV 322

  Fly   315 VGPRLPRKLLLCLSSLFAAAAVIALALFKAYGHLWLLG------NWADRYLPIILLAIQLALVSF 373
            :..||.||:||.:|::.......|:.   .|.:..:||      :|    :||...:..|.|.:.
  Fly   323 LVERLGRKILLLVSAVGIGLGQSAMG---TYSYFQMLGCPVASFSW----VPIAGFSFMLFLAAV 380

  Fly   374 GLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLFGMIEAFNAVKA----TIAPGLLLYLWVFAG 434
            ||..|..:|.||::|.|:......:..:..||:      :..|||.    |.:.|:...:::||.
  Fly   381 GLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLI------STCAVKLMPVFTESLGMHGTVFMFAS 439

  Fly   435 ASIFVGLISLPLLPETRNRRPSAVQREL 462
            .|....:.....:|||:.:...|:...|
  Fly   440 LSFLAAIFIAIFVPETKGKSVDAILASL 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	43/137 (31%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	112/421 (27%)
CG33281	NP_995620.1	MFS	50..452	CDD:119392	110/420 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004527
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740