back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and Slc2a4

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_033230.2	Gene:	Slc2a4 / 20528	MGIID:	95758	Length:	509	Species:	Mus musculus

Alignment Length:	517	Identity:	124/517 - (23%)
Similarity:	209/517 - (40%)	Gaps:	99/517 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KRVGGPAIQSVATA-LGNILCFNFGLMFGITPAHMTLYESE-------ERTPLNQATDPAGTAWL 61
            :||.|..:.:|.:| ||::   .||...|:..|...:.|..       .:.|....:.|.||  |
Mouse    18 QRVTGTLVLAVFSAVLGSL---QFGYNIGVINAPQKVIEQSYNATWLGRQGPGGPDSIPQGT--L 77

  Fly    62 TGYLFLSAAL---GALVSGFL----ALKIGPKSVLLCSGLLQISGWACIHF-----GYDIVHIYA 114
            |....||.|:   |.::|.||    :..:|.|..:|.:.:|.:.|.|.:..     .|:|  :..
Mouse    78 TTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLANNVLAVLGGALMGLANAAASYEI--LIL 140

  Fly   115 SRLFAGVASGAAFVVLPIFINEIAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVGC 179
            .|...|..||....::|:::.|||.:..:.|..|.. :|...:|||:..|||      ..:::|.
Mouse   141 GRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLN-QLAIVIGILVAQVLG------LESMLGT 198

  Fly   180 AV------------SFVFTMTFPFVQESPHY-YLRKNNMASLEKSLRWYRGIRDIDDREKPEYLS 231
            |.            :.:..:..||..|||.| |:.:|......|||:...|..|:.|.     |:
Mouse   199 ATLWPLLLALTVLPALLQLILLPFCPESPRYLYIIRNLEGPARKSLKRLTGWADVSDA-----LA 258

  Fly   232 ELNEFHAELRSRDKNVGSTPMSHGYIIRL---------TFVSFLLTVCAKLSGVFVELNYAADF- 286
            ||.:   |.|..::   ..|||   :::|         ..::.:|.:..:|||:.....|:...
Mouse   259 ELKD---EKRKLER---ERPMS---LLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIF 314

  Fly   287 ----LGRTGYSTETNYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALALFKAYGH 347
                :|:..|:|....||.........||....|.|...  ||.|:.:...|.::.:||
Mouse   315 ESAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLH--LLGLAGMCGCAILMTVAL------ 371

  Fly   348 LWLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLFGMIE 412
            |.|....|..|:.|:.:...:|....|..|:...:.:|:..........::|...:|...|.:..
Mouse   372 LLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTCNFIVGM 436

  Fly   413 AFNAVKATIAPGL-LLYLWVFAGASIFVGLISLPLLPETR-----------NRRPSAVQREL 462
            .|..|...:.|.: ||:..:..|..||..|    .:||||           .|.||.:::|:
Mouse   437 GFQYVADAMGPYVFLLFAVLLLGFFIFTFL----KVPETRGRTFDQISAAFRRTPSLLEQEV 494

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.