DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_006505885.1	Gene:	Slc2a3 / 20527	MGIID:	95757	Length:	495	Species:	Mus musculus

Alignment Length:	501	Identity:	107/501 - (21%)
Similarity:	186/501 - (37%)	Gaps:	78/501 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ATALGNILCFNFGLMFGITPAHMTL------YESEERTPLNQATDPAGTAWLTGYLFLSAA---- 70
            |..:..|..|.||...|:..|..|:      |..|||     ..|......||....|..|
Mouse    15 AVTVATIGSFQFGYNTGVINAPETILKDFLNYTLEER-----LEDLPSEGLLTALWSLCVAIFSV 74

  Fly    71 ---LGALVSGFLALKIGPKSVLLCSGLLQISGWACIHF---GYDIVHIYASRLFAGVASGAAFVV 129
               :|:...|....:.|.::.:|...||.|.....:.|   ...:..:...||..|:..|.....
Mouse    75 GGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGF 139

  Fly   130 LPIFINEIAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFV--------NIVGCAV--SFV 184
            :|::|.|::.:..:.|..|.     ..|||::|.::.......|:        .::|..:  :.:
Mouse   140 VPMYIGEVSPTALRGAFGTL-----NQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAIL 199

  Fly   185 FTMTFPFVQESPHYYL---RKNNMASLEKSLRWYRGIRDIDDREKPEYLSELNEFHAE--LRSRD 244
            .:...||..|||.:.|   ::.:.|:......|  |..|:        :.|:.|...|  ..|::
Mouse   200 QSAALPFCPESPRFLLINKKEEDQATEILQRLW--GTSDV--------VQEIQEMKDESVRMSQE 254

  Fly   245 KNVGSTPM--SHGYIIRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTG-----YSTETNYVVLA 302
            |.|....:  |..|:..| .:|.:|.:..:|||:.....|:.......|     |:|....||..
Mouse   255 KQVTVLELFRSPNYVQPL-LISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNT 318

  Fly   303 SAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALALFKAYGHLWLLGNWADRYLPIILLAIQ 367
            ........|....|.|....:.|...::.:....|:|.|...|.        |..::.|:.:.|.
Mouse   319 IFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDDYE--------AMSFVCIVAILIY 375

  Fly   368 LALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWL--LLFGMIEAFNAVKATIAPGLLLYLW 430
            :|....|..|:...:.:|:..........::|...:|.  .|.||:  |.:..|.:  |..:::
Mouse   376 VAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGML--FPSAAAYL--GAYVFI- 435

  Fly   431 VFAGASIFVGLISLPLLPETRNRRPSAVQREL-GYVDDGGVAKGSA 475
            :||...||..:.:...:|||:.|....:.|.. |....|   ||.|
Mouse   436 IFAAFLIFFLIFTFFKVPETKGRTFEDIARAFEGQAHSG---KGPA 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	29/157 (18%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	87/428 (20%)
Slc2a3	XP_006505885.1	MFS_GLUT_Class1	14..458	CDD:340989	100/476 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834189
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840