DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and F11D5.7

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001367751.1	Gene:	F11D5.7 / 184345	WormBaseID:	WBGene00043980	Length:	521	Species:	Caenorhabditis elegans

Alignment Length:	513	Identity:	94/513 - (18%)
Similarity:	183/513 - (35%)	Gaps:	110/513 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IQSVATALGNILCFNFGLMFGITPAHMTL-YESEERTPLNQ------------ATDPAGTAWLTG 63
            :..:.|.:.|   ......|||.|....| :.:...|..||            ..|..|..::..
Worm    33 LSEIITEMNN---HTLSTHFGIVPTETKLSFVNSIITTSNQVGNALSILLLLPVVDYKGRKFVAV 94

  Fly    64 YLFLSAALGALVSGFLALKIGPKSVLLCSGLL---QISGWACIHFGYDIVHIYASRLF------- 118
            ||..:......:...||.......|.:....|   |.|           :..:|:::|
Worm    95 YLRFALIFSTGICHLLAALFQASEVFILGQFLLGVQTS-----------LRFFATQMFIVESSPD 148

  Fly   119 --AGVASGA---AFVVLPIFINEIAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVG 178
              .|.||.:   |||     |:::......:..|..|.:||        |:      |....::.
Worm   149 NCRGFASASLAFAFV-----ISKLVMFSSSSPSLLGTSDLW--------FI------YPVFEMIT 194

  Fly   179 CAVSFVFTMTFPFVQESPHYYLRKNNMASLEKSLRWYRGIRDIDDREKPEYLSELNEFHAELRSR 243
            ..:.|...:..|   |||.:.::::.:...:.|:::|.|.:...|.....::.|.|..:....|.
Worm   195 ATIIFCLMLHLP---ESPKWLIQQDKLDEAKMSIKFYHGKKCTIDEIVTSFIKERNLTNKNKISL 256

  Fly   244 DKNVGSTPMSHGYIIRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTE----TNYV---VL 301
            .:...:..:..|..|....:.||     :....:|...|..||....|::.:    .|.:   ||
Worm   257 KEVWDNETLREGLKIVFAVLLFL-----EFDTSYVTSVYTIDFHKSAGFTVQQALNINLIITTVL 316

  Fly   302 ASAQCAGALLARLVGPRLPRKLLLCLSSL--FAAAAVIALA--LFKAYGHLWLLGNWADRYLPII 362
            ...:..|..|...:|    |:.:|.::.:  |:.:.:|...  :..|:|..||     .|.:.::
Worm   317 FPTKFIGTFLLDALG----RRPVLAIAGIIQFSRSCLILSVEIIIYAFGSSWL-----TRIMFVV 372

  Fly   363 LLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLFG-------MIEAFNAVKAT 420
            :.::.....:.|:..:..:::.|:.|:       |..:.|....|||       ::..|..:.:.
Worm   373 VESLSPIASATGVNSIRLLLTMELFPS-------SARTVVGQAKLFGSMLIGTPIVSLFPIINSL 430

  Fly   421 IAPGLLLYLWVFAGASIFVGLISLPLLPETRNRRPSAVQRELGYVDDGGVAKGSAVTN 478
            ..|   ::...|....:.:|:.....:||||.|....:...|    |..||..:|..|
Worm   431 FPP---IFFVPFVITQLLLGIYLFRHMPETRGRAVYDIIESL----DRNVASRAASIN 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	27/152 (18%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	75/427 (18%)
F11D5.7	NP_001367751.1	MFS	34..460	CDD:421695	87/485 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157957
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930