Protein Alignment CG8837 and hmit-1.1

DIOPT Version :10

• Sequence 1: NP_608764.1
• Gene: CG8837 / 33545
• FlyBaseID: FBgn0031520
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 119/564 - (21%)
• Similarity: 203/564 - (35%)
• Gaps: 158/564 - (28%)

  Fly    12 IQSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYLFLS---AALGA 73
            |.:.|:.:|..|   ||....:..|.| ||     .|......|..|.|....:.:|   ||:|:
 Worm    27 ILAAASVIGGFL---FGYDTSVVSAAM-LY-----MPDAPGLKPMDTVWQEVLVSISPGMAAVGS 82

  Fly    74 LVSGFLALKIGPKSVLL-CSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEI 137
            |:||..:..||.:.|:| .|.:..|....|. ...:.:.:...|:..|:|.|.|.:::|:::.|.
 Worm    83 LMSGTSSDYIGRRKVILGASAIFTIGALVCA-ASVNKIMLLVGRVLLGIAIGFASMIVPVYLGET 146

  Fly   138 AESREK---AARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVGCAVSFVFT--------MTFPF 191
            |.:..:   .|.....|...:.:..:.|....:..||.    ||..:.|.|.        :.|.|
 Worm   147 APTHVRGMLVAAFALMISFGQVVANITGGAFSYIDPYN----VGWRLMFAFAAVPSIIQFVCFMF 207

  Fly   192 VQESPHYYLRKNNMAS-----LEKSLRWYRGIRDIDDREKPEY-LSELNEFHA-ELRSRDKNVGS 249
            :.|:|. :|.:|...:     |||.   |.|     |:|..|| ::|:..|:. :.:..:|...|
 Worm   208 LPETPR-WLYENGFETETREVLEKV---YNG-----DKEWVEYEMAEIIAFNEDQAKENEKAHAS 263

  Fly   250 TP-----MSHGYIIRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTETNYV---VLASAQC 306
            .|     :...::::..|:..:|....:|:|:...|.|.||.:..:|.|.....:   ||.|
 Worm   264 GPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSSGISNNHTTIWISVLLS--- 325

  Fly   307 AGALLARLVGPRLPRKLLLCLSS----LFAAAAVIALALFKAYGHLWLLGN-------------- 353
                |...:||.:|..|:..:..    ||:...|:...:|  .|..:||.|
 Worm   326 ----LCNFIGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVF--IGVAFLLVNHDSAATLPANQYGS 384

  Fly   354 ----------------------------------------------------------------- 353
                                                                             
 Worm   385 NFNSSYPDAKGCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYSSTGSCTNSNGSIA 449

  Fly   354 ----WADRY-------LPIILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLL 407
                |...|       ||||...:.|...|.|...|..|::||..|........::::..:|  :
 Worm   450 NNFKWEKYYCDTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARSTCVAISTTSNW--V 512

  Fly   408 FGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISLPLLPETR 451
            |.:|.|...:..|...|.....|::||.::...:..|.|:|||:
 Worm   513 FNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETK 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_608764.1	MFS_GLUT6_8_Class3_like	15..457	CDD:340916	118/561 (21%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	115/556 (21%)