DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8837 and Slc2a13

DIOPT Version :9

Sequence 1:NP_001285582.1 Gene:CG8837 / 33545 FlyBaseID:FBgn0031520 Length:485 Species:Drosophila melanogaster
Sequence 2:NP_598295.2 Gene:Slc2a13 / 171147 RGDID:621814 Length:637 Species:Rattus norvegicus


Alignment Length:565 Identity:118/565 - (20%)
Similarity:191/565 - (33%) Gaps:151/565 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 PAIQSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYLFLSAALG-- 72
            ||....|.|...:..|.||...|:....|.|...:.|         .|..|..  |.:|.|:|  
  Rat    67 PAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQMR---------LGAMWQE--LLVSGAVGAA 120

  Fly    73 ---ALVSGFLALKIGPKSVLLCSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFI 134
               ||..|.|...:|.:|.:|.:..|...|.|.:....:...:.|.||..|:..|.|.:.:|::|
  Rat   121 AVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYI 185

  Fly   135 NEIAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNI--------VGCAV--SFVFTMTF 189
            .|::....:...:|.     .||.|..|......|..||..:        :|.|.  :.:..:.|
  Rat   186 AEVSPPNLRGRLVTI-----NTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGF 245

  Fly   190 PFVQESPHYYLRKNNMASLEKSLRWYRGIRDIDDREKPEYLSELNEFHAELRSRDKNVGSTPMSH 254
            .|:.|||.:.::|.......:.|...||.:.||:    ||.|..|....|    :|...:.    
  Rat   246 LFLPESPRWLIQKGQTQKARRILSQMRGNQTIDE----EYDSIRNSIEEE----EKEASAA---- 298

  Fly   255 GYII----------RLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTETNYVVLASAQCAGA 309
            |.||          |...|...|.:..:|||:...:.|:|..|..:|...:...:.|||......
  Rat   299 GPIICRMLSYPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTN 363

  Fly   310 LLARLVGPRLPRKL------------------LLCLSSLFAA----------------------- 333
            .:..|||..|..|:                  :|.|..|.:|                       
  Rat   364 FIFTLVGVWLVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEY 428

  Fly   334 --------------------AAVIALAL---------------------FKAYGHLWLLGNWADR 357
                                :|||..:.                     |||....|........
  Rat   429 SYCNECMLDPDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTP 493

  Fly   358 YLPIILLAIQLALVSF--GLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLFGMIEAFNAVKAT 420
            |....|:.:.|.||.|  |:.|:...|:||:.|........:.::.::|:        ||.:.:.
  Rat   494 YSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWI--------FNVLVSL 550

  Fly   421 IAPGLLLYLWVFAGASIFVGLISLPL------LPETRNRRPSAVQ 459
            .......||..:....::.|..::.|      ||||:.::...::
  Rat   551 TFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIE 595

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8837NP_001285582.1 MFS 54..>192 CDD:119392 36/152 (24%)
Sugar_tr 58..453 CDD:278511 106/509 (21%)
Slc2a13NP_598295.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 16..38
MFS 75..580 CDD:119392 111/540 (21%)
Sugar_tr 78..598 CDD:278511 114/554 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337782
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0254
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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