DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and AgaP_AGAP008721

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_314829.4	Gene:	AgaP_AGAP008721 / 1275572	VectorBaseID:	AGAP008721	Length:	502	Species:	Anopheles gambiae

Alignment Length:	509	Identity:	123/509 - (24%)
Similarity:	202/509 - (39%)	Gaps:	84/509 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LPKRVGGPAIQSVATALGNILCFNFGLMFGI-TPAHMTLYESEERTPLNQATDPAGTAWLTGYLF 66
            |.||..  ..|.:|..:.||...:.|:..|. :.|.|.|..|.....|.::.    .:|......
Mosquito    22 LTKRAA--ITQIIAAVVANITIISSGMGIGFPSIAMMELTNSTTSVVLTESE----ASWFASISS 80

  Fly    67 LSAALGALVSGFLALKIGPKSVLLCSGLLQISGWA----CIHFGYDIVHIYASRLFAGVASGAAF 127
            .:..||.||||:|..:||.|..|:...:|.|..||    |....:|:  :|...|.|.|..|...
Mosquito    81 FACPLGGLVSGYLLDRIGRKKTLMLINVLSIVSWALIAVCSTTNFDL--MYTQILIARVVIGLVS 143

  Fly   128 VVLPIFINEIAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVG-----CAVSFVFTM 187
            ....|:..|||..:.: .|||....|...:|||:.:.:|:.||..|..:.|     |.:|....:
Mosquito   144 APASIYSAEIATPKMR-GRLTVLTSLSIAVGILLIYSMGYAVPDDFRLVAGLAAGICVLSLALLL 207

  Fly   188 TFPFVQESPHYYLRKNNMASLEKSLRWYRGIRDIDDREKPEYLSELNEFHAELRSRDKNVGSTPM 252
               |:.|||.:.:.|:.....|:||:..||......| .||...||      :|.||..:.....
Mosquito   208 ---FMPESPAWLMSKDREEEAERSLKKIRGYGAYSQR-IPEVEKEL------MRMRDNVLAQRRA 262

  Fly   253 SHGYIIRLT--------------FVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTETNY--VVL 301
            .....:||.              |..|     .:.||:||.:.|||........|.:...  |::
Mosquito   263 GQESFLRLLKQPQVYKPLGIIIGFFGF-----QQFSGIFVIVVYAAKVSSEASVSMDPFLCTVLI 322

  Fly   302 ASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALALFKAYGHLWLLGNWADRYLPIILLAI 366
            ...:....:|...:...|.||.....|.:.....:..|||...:..:..| ||    :|.:|:..
Mosquito   323 GITRVVATMLVAYILDTLGRKPPSIFSGVGMLVCMFGLALCSYFPPIESL-NW----IPTVLILT 382

  Fly   367 QLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLFGMIEAFNAVKATIAPGLLLYLWV 431
            .:...:.|...:...:.:|:.|..:.    ..||.|:  :.|..:.:|..:|  :.|.::..|
Mosquito   383 YIFTSTLGFLTMPFSMLAELFPQAVR----GPASGVT--VFFTYLMSFCTIK--LYPTMVELL-- 437

  Fly   432 FAGASIFV--GLISL-------PLLPETRNRRPSAVQRELGYVDD--GGVAKGS 474
             ..|::|:  |.:||       .::|||:.       :.|..::|  .|::.||
Mosquito   438 -GSANVFLIYGAVSLLGVLYVIYIVPETKG-------KSLQEIEDYFRGMSHGS 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	41/146 (28%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	104/428 (24%)
AgaP_AGAP008721	XP_314829.4	MFS	35..461	CDD:119392	110/463 (24%)
AgaP_AGAP008721	XP_314829.4	Sugar_tr	58..473	CDD:278511	108/459 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810