DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and AgaP_AGAP003493

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_003436496.1	Gene:	AgaP_AGAP003493 / 1270939	VectorBaseID:	AGAP003493	Length:	482	Species:	Anopheles gambiae

Alignment Length:	468	Identity:	113/468 - (24%)
Similarity:	200/468 - (42%)	Gaps:	31/468 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GGPAIQSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYLFLSAALG 72
            |.|:.|.:|..:.|:.....|...|.|......:.|::.|||:.....:.::|:...:.:.|.:.
Mosquito    29 GSPSRQFMAGIIVNLASVMVGTSLGWTSPVGPKFASKDTTPLDTIPTASESSWIASLVAMGALIA 93

  Fly    73 ALVSGFLALKIGPKSVLLCSGLLQISGWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEI 137
            ..::|.||.:||.|..||.|.:..:..:..:.....:|.:..:|...|:..|....|..::|.||
Mosquito    94 PFIAGPLAERIGRKFTLLGSSIFFLVSFILLLTTETVVQVLIARFIQGLGVGFVMTVQTMYIGEI 158

  Fly   138 AESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVGCAVSFVFTMTFPFVQESPHYYLRK 202
            | |.|....|...::|....|||..:.:|.||.|..:......:...|..||.|:.|:|.||:.|
Mosquito   159 A-SNEYRGALGSLMQLCIVTGILYVYSIGPYVSYHALQWACIVLPIAFDATFFFMPETPAYYISK 222

  Fly   203 NNMASLEKSLRWYRGIRDIDDREKPEYLSELNEFHAELRSRDKNVGSTP---MSHGYIIRLTFVS 264
            .:.....:||.:.|| :.:|..::     ||:|....:....:|.||..   .:.|.:..|...:
Mosquito   223 GDKEKAVESLCFLRG-KTVDGVQE-----ELHEISTTVEESLRNKGSVMDLFRNAGNVKALIICA 281

  Fly   265 FLLTVCAKLSGVFVELNYAADFLGRTG--YSTETNYVVLASAQCAGALLARLVGPRLPRKLLLCL 327
            .|::. .:|||:.|.|.|:.:....||  .|...:.:::.:.|...:....|:..||.||.:|..
Mosquito   282 GLISF-QQLSGINVILFYSQNIFESTGSSLSPAVSTILVGAVQVLASGATPLIVDRLGRKPILLT 345

  Fly   328 SSLFAAAAVIALALFKAYGHLW--------LLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSS 384
            |   |....|:|.....|..|.        .||     :|||:.|.:.:.:...|..||...|..
Mosquito   346 S---AGGMCISLGTMGLYFFLKHTESPSVDSLG-----WLPIMSLIVFVTVYCIGFGPLPWAVLG 402

  Fly   385 EVLPTKLHDLLYSLASAVSWLLLFGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISLPLLPE 449
            |:.|..:..:..|:.::..|:|.|.:::.|..:...:  |.....|:|........:.:...|.|
Mosquito   403 EMFPANVKSIASSIVASTCWVLGFIILQFFADLDKAV--GSHWSFWIFGILCAVAFVFTFTTLME 465

  Fly   450 TRNRRPSAVQREL 462
            |:......:|..|
Mosquito   466 TKGLSLQEIQDRL 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	34/137 (25%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	99/407 (24%)
AgaP_AGAP003493	XP_003436496.1	MFS	39..460	CDD:119392	104/438 (24%)
AgaP_AGAP003493	XP_003436496.1	Sugar_tr	71..475	CDD:278511	99/421 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910