DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001095884.1	Gene:	Slc2a9 / 117591	MGIID:	2152844	Length:	538	Species:	Mus musculus

Alignment Length:	519	Identity:	124/519 - (23%)
Similarity:	200/519 - (38%)	Gaps:	96/519 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCLPKRVGGP-------------------AIQSVATALGN--ILCFNFGLMFGITPAHMTLYESE 44
            ||   ..|||                   .:.::..|.|:  :..:|..::...||.....|...
Mouse    12 MC---DTGGPGELSVGHQQRRTKKWSFSLVVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNGT 73

  Fly    45 ERTPLNQATDPAGTAWLTGYLFLSAALGALVSGFLALK-----IGPKSVLLCSGLLQISG---WA 101
            ......|..||.....|........|:|.|| |.|.:|     :|.||.||.:....||.   .|
Mouse    74 WYRRHGQPIDPDTLTLLWSVTVSIFAIGGLV-GTLMVKMIGKFLGRKSTLLVNNGFAISAALLMA 137

  Fly   102 CIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEIA--ESREKAARLTFTIELWRTLGILIGFV 164
            |.........:...|...||..|.|...||:::|||:  |.|....::|   .::..:|:..|.:
Mouse   138 CSLRAGTFEMLIVGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQVT---AIFICIGVFSGQL 199

  Fly   165 LGF--------YVPYAF-VNIVGCAVSFVFTMTFPFVQESPHYYL-RKNNMASLEKSLRWYRGIR 219
            ||.        ..||.| |.||...|...   :.||:.|||.|.| .|::.|...|:.:.:.|..
Mouse   200 LGLPELLGRESTWPYLFGVIIVPALVQLA---SLPFLPESPRYLLFEKHDEAGAMKAFQTFLGKA 261

  Fly   220 DIDDREKPEYLSELNEFHAELRSRDKN---VGSTPMSHGYIIRLTFVSFLLTVCA-KLSGVFVEL 280
            |:.        .||.|..||.|.: :|   |....:.....:|...::.::|:.: :|.|:....
Mouse   262 DVS--------QELEEALAESRVQ-RNLRLVSVLELLRAPFVRWQVITVIITMASYQLCGLNAIW 317

  Fly   281 NYAADFLGRTGY-STETNYVVLASA--QCAGALLARLVGPRLPRKLLLC----LSSLFAAAAVIA 338
            .|.....|:.|. ..:..|:.|::.  :...|:.:.||..||.|:.||.    |.:||.......
Mouse   318 FYTNSIFGKAGIPQDKIPYITLSTGGIETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGTLTAT 382

  Fly   339 LALFKAYGHLWLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVS 403
            |.|...       ..|.. ||.|:.:...:|....|...:..:::.|..........:.:|..|:
Mouse   383 LTLQDQ-------APWVP-YLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFMIAGTVN 439

  Fly   404 WL------LLFGMIEAFNAVKATIAPGLLLYLWV-FAGASIFVGLISLPLLPETRNRRPSAVQR 460
            ||      |||..|:     |:..:...|::..: .|||:.|..     :||||:||..:.:.:
Mouse   440 WLSNFAVGLLFPFIQ-----KSLDSYCFLVFATICIAGATYFYF-----VLPETKNRTHAEISQ 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	44/156 (28%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	108/432 (25%)
Slc2a9	NP_001095884.1	MFS_GLUT_Class2	40..491	CDD:340990	119/484 (25%)
Slc2a9	NP_001095884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..538
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834225
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840