DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and CG42826

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001189079.1	Gene:	CG42826 / 10178905	FlyBaseID:	FBgn0262008	Length:	473	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	120/516 - (23%)
Similarity:	189/516 - (36%)	Gaps:	132/516 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PKRVGGPAIQSVA------------------TALGNI--------LCFNFGLMFGITPAHMTLYE 42
            ||:...|...|:|                  ||||:.        :...:|..|.:..||.   :
  Fly     3 PKKCEPPPEDSLATTEKATFLRLGHKNHSQWTALGSASFILISGGMSLAWGAGFAVHSAHR---D 64

  Fly    43 SEERTPLNQATDPAGTAWLTGYLFLSAALGALVSGFLALKIGPKSVLLCSGLLQI-SGWACIHFG 106
            ...||...|      .||     :.:|.||||...|...::..:.:.:.|.:|.| ||...:.:.
  Fly    65 QLLRTVHMQ------IAW-----YATAVLGALFGAFYTHRLPQQPIYIFSSILVIASGILFLAWP 118

  Fly   107 YDIVHIYASRLFAGVASGAAFV-----VLPIFINEIAESREKAARLTFTIE-LWRTLGILIGFVL 165
            .....|.|:|...|:|:|..||     |..|.:|||      ...|..|:| |....|||:..:
  Fly   119 ECPGAIIAARYLDGLANGLVFVPALSTVGEISVNEI------RGLLASTVEQLSFNTGILLQLI- 176

  Fly   166 GFYVP---------------YAFVNIVGCAVSFVFTMTFPFVQESP-HYYLRKNNMASLEKSLRW 214
              |..               :..::||...::....:|  ...||| |..:|.:...:|.
  Fly   177 --YTAVWQVDWNVAIVADQVHGVLSIVYGVIALALALT--LCVESPVHLLMRSSEQRALV----- 232

  Fly   215 YRGIRDIDDREKP-----EYLSELNEFHAE--LRSRDKNVGSTPMSHGYIIRLTFVSFLLTVCAK 272
              .:|.:   ::|     |.|..|:| |.:  ..:|:..:||: :..||      .|.|..:..:
  Fly   233 --ALRHL---QRPYMVTSEMLLRLDE-HKQYVADNREMCLGSS-LQKGY------PSVLKLLALR 284

  Fly   273 LSGVFVELNYAADFLGRTGYSTET-----NYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFA 332
            |.||....:.....|..||....:     .:||....:..|...|.|:.....||    ..:||.
  Fly   285 LLGVLSLNSIICSALYETGNQLVSCLYAWPFVVFGLLRWGGCFFAVLLMDTTGRK----KPTLFG 345

  Fly   333 AAAVIALALFKAYGHLWLLGNWADRYLPIILLAIQLALVSF--GLYPLA-AVVSSEVLP--TKLH 392
            ..:..|.|:  ||.:|:      .|...:|...:.|..:.|  ||...| ||..:|..|  .|.|
  Fly   346 IFSTGAFAI--AYANLF------GRTPHMITALVMLFSLQFFEGLGQCASAVYLTEGFPLLMKPH 402

  Fly   393 --DLLYSLASAVSWLLLFGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISLPLLPETR 451
              .::|.:..|.. |||...:.:...:.|        |.......|:...|:.:..|||||
  Fly   403 MVAVVYIMEQAAR-LLLCSFLPSIAEITA--------YFHSMGALSMVCFLLGIFCLPETR 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	37/159 (23%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	104/436 (24%)
CG42826	NP_001189079.1	Sugar_tr	80..465	CDD:278511	102/425 (24%)
CG42826	NP_001189079.1	MFS	310..>459	CDD:119392	41/166 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444371
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740