Protein Alignment Fign and PEX6

DIOPT Version :9

• Sequence 1: NP_001259995.1
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_014070.1
• Gene: PEX6 / 855387
• SGDID: S000005273
• Length: 1030
• Species: Saccharomyces cerevisiae
• Alignment Length: 561
• Identity: 150/561 - (26%)
• Similarity: 249/561 - (44%)
• Gaps: 114/561 - (20%)

  Fly    62 TKRGIT-HAGYLFEMPHNSVFEPECRGF---YESCQQTEMASSDLQAPALEVSSTYPVQQAVKSR 122
            ::|||| :|..|.....|:|.:.....|   |......|:....|.:.:.::.||..:...::::
Yeast   468 SQRGITLNASVLLHSTTNNVGKATMVRFASKYLGIHLLEIDCLSLTSNSRQLDSTSKIIGYIRAK 532

  Fly   123 PEGQFPESR---------NNSTKKIDAQQYSSESSSQSGFGFRTAREQLIMDELKKKNRQAT--- 175
            .|...|.:.         ::....::|.|.......|....|..::   ::|:...|....|
Yeast   533 CENVLPYASPAVIFLAHLDSILLDVNANQDPEAIKLQKSINFEMSK---LLDDFTFKFPGTTFVG 594

  Fly   176 --SEVDAVPTGMMNFRKKTL------GGKRT------VSSNFVS-------PVAQNDNSTSSRSS 219
              :.:|.||:...:..:..:      ..:|.      :||:.::       ||:..||.:.|..|
Yeast   595 SVNNIDNVPSSFRSHMRFEILVPVPSEAQRLRIFQWYLSSHELNRDVQQKVPVSYMDNISFSSLS 659

  Fly   220 SIPPALAHLDSKMV-----------------------DHIL----------GESMHDFK------ 245
            |....|..||.|.:                       ..||          .::.::|.
Yeast   660 SYSAGLTPLDIKSIVETARMTATARFYQESKKCGWLPQSILITQEDLSKATSKARNEFSVSIGAP 724

  Fly   246 ---PVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQA 307
               .|.|:||.|::..|...|:.|.|||:.|:|||.......|:|.:|||||||||:||:||:..
Yeast   725 QIPNVTWDDIGGIDFVKGEILDTIDMPLKHPELFTSGMKKRSGILFYGPPGTGKTLMAKAIATNF 789

  Fly   308 KAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENES---TLRL 369
            ...|||:....|.:.::|::|..|:.:|..|...:|.:||.||:||:..|| .|:.:|   ..|:
Yeast   790 SLNFFSVKGPELLNMYIGESEANVRRVFQKAREAKPCVIFFDEIDSVAPKR-GNQGDSGGVMDRI 853

  Fly   370 KNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTREARQ-KIIEKLIH 431
            .::.|..|||.:::.: .|.||||||||..||||:.|  ||.:.||:.:|..:.:| .|:|.|..
Yeast   854 VSQLLAELDGMSTDAD-GVFVIGATNRPDLLDEALLRPGRFDKLLYLGIPDTDTKQLNILEALTR 917

  Fly   432 QVKHNLDVRQVIELAELTD-GYSGADVDTLC---------RYASMAPLRSLTPDQM--EVIETHQ 484
            :...:.||: :||||:|.. .|:|||...||         |.|.|...:....:::  |.|.|.:
Yeast   918 KFVLDNDVK-LIELAKLCPFNYTGADFYALCSDAMLNAMSRIARMVEKKVSQHNELTGENISTRR 981

  Fly   485 -----------LPAVTMDDFKQALRVISKSVSSEDCKQFEA 514
                       ...|.|:||.:|...::.|||..:...:||
Yeast   982 WFDKIATKEDTKVVVKMEDFLKAQEQLTPSVSRAELNHYEA 1022

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	58/140 (41%)
		AAA	286..416	CDD:278434	57/134 (43%)
		Vps4_C	<480..520	CDD:286426	12/46 (26%)
PEX6	NP_014070.1	SpoVK	540..1017	CDD:223540	132/482 (27%)
		RecA-like_PEX6_r2	740..899	CDD:410935	67/160 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810