Protein Alignment Fign and PEX1

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_196464.2
• Gene: PEX1 / 830746
• AraportID: AT5G08470
• Length: 1130
• Species: Arabidopsis thaliana
• Alignment Length: 541
• Identity: 135/541 - (24%)
• Similarity: 228/541 - (42%)
• Gaps: 85/541 - (15%)

  Fly    27 HFAALKD--HHARLQACESMEKAMKERCQKKITMSRRTKRGITHAGYLFEMPHNSVFEPECRGFY 89
            :|...||  .|..|.:|.::  |:::.......:|.....|:.||      |...:.: :.....
plant   616 YFEEQKDLLAHVILVSCSTL--ALEKVQHIHHVLSSVIAEGLEHA------PSVIILD-DLDSII 671

  Fly    90 ESCQQTEMASSDLQAPALEVSSTYPVQQAVKSRPEGQFPESRNNS--------TKKIDAQQYSSE 146
            .|...||...:.:....|....|..:.         .:.|.||:|        ...:.:.:...:
plant   672 SSSSDTEGTQASVGVTMLTKFLTDVID---------DYGEYRNSSCGIGPLAFVASVQSLEQIPQ 727

  Fly   147 SSSQSG-FGFR--------TAREQLIMDELKKKNRQATSEVDAVPTGMMNFRKKTLGGKRTVSSN 202
            :.|.|| |.|.        :.|..::..|::|:....:.::      ::|...|..|........
plant   728 TLSSSGRFDFHVQLAAPATSERGAILKHEIQKRLLDCSEDI------LLNLAAKCEGYDAYDLEI 786

  Fly   203 FVSPVAQNDNSTSSRSSSIPPALAHLDS-KMVDHILGESMHDFKPVA---------------WED 251
            .|      |.:..:......|..:::.. .:|......:||||.|||               |||
plant   787 LV------DRAVHAAIGRHLPLESNISKYNLVKEDFTRAMHDFVPVAMRDITKSASEGGRLGWED 845

  Fly   252 IAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPR---GVLLFGPPGTGKTLIAKSIASQAKAKFFS 313
            :.|:...|:...|.|.:|.:.|.:|  .:.|.|   .|||:||||.|||.|..:.|:....:|.|
plant   846 VGGVTDIKNAIKEMIELPSKFPKIF--AKSPLRLRSNVLLYGPPGCGKTHIVGAAAAACSLRFIS 908

  Fly   314 INPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEFLIHLD 378
            :....|.:|::|.:|:.|:.:|:.|||..|.|:|.||.||:..||..:....|.|:.|:||..||
plant   909 VKGPELLNKYIGASEQAVRDIFSKAAAAAPCILFFDEFDSIAPKRGHDNTGVTDRVVNQFLTELD 973

  Fly   379 GAASNEEI--RVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTREARQKIIEKLIHQ--VKHNL 437
            |.    |:  .|.|..||:||..||.|:.|  |..|.|....|:...|.:|:..|..:  :..::
plant   974 GV----EVLTGVFVFAATSRPDLLDPALLRPGRLDRLLLCDFPSPPERLEILTVLSRKLLMADDI 1034

  Fly   438 DVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISK 502
            |:..:   |.:|:|:||||:..|...|.:|.:.... ::.:..||...|.:|....|........
plant  1035 DLEPI---ALMTEGFSGADLQALLSDAQLAAVHEYL-NREDKPETGTTPIITDPLLKSIASKTKP 1095

  Fly   503 SVS-SEDCKQFEAWNEIYGVR 522
            ||| :|..|.::.:::....|
plant  1096 SVSETEKQKLYDIYSQFLDSR 1116

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	7/24 (29%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	74/207 (36%)
		AAA_lid_3	444..495	CDD:465537	14/50 (28%)
		Vps4_C	<480..520	CDD:462762	10/40 (25%)
PEX1	NP_196464.2	PEX-1N	109..182	CDD:462729
		CDC48	<585..1117	CDD:273521	135/541 (25%)
		RecA-like_PEX1_r2	852..1009	CDD:410934	62/162 (38%)