Protein Alignment Fign and IQCA1

DIOPT Version :9

• Sequence 1: NP_001259995.1
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001257514.1
• Gene: IQCA1 / 79781
• HGNCID: 26195
• Length: 830
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 101/526 - (19%)
• Similarity: 204/526 - (38%)
• Gaps: 132/526 - (25%)

  Fly    42 ESMEKAMKERCQKKITMSRRTKRGITHAGYLFEMPHNSVFEPECRGFYESCQQTEMASSDLQAPA 106
            |...|..|::.:|:...:::.|:|.....                  .|..::.:|:.| |..||
Human   356 EEKNKKKKKKKEKQPKKAKKQKKGTKEKN------------------KEEDEKWKMSPS-LFLPA 401

  Fly   107 L-EVSSTYPVQQAVKSRPEGQFPESRNNSTKKIDAQQYSSESSSQSGFGFRTAREQLIMDELKKK 170
            : |..:.|  ::....:.|..      |.::..|.:....|...:.....|...::|:..|||..
Human   402 MKEGCNAY--KEIWMKKDESW------NFSQDYDPELIKEEKRKELQSEIRIQVDELMRQELKNL 458

  Fly   171 NRQATSEVD-AVPTGMMNFRKKTLGGK---------------RTVSSNFVSPVAQ---------- 209
            ......|.: .|..|....:||...||               ||:.|.:...|.:
Human   459 KLAVDRERERPVKAGKKKDKKKGKKGKKKEKKAKKDKDLTADRTIESLYKELVEEGLLIQALKVN 523

  Fly   210 -NDN-------STSSRSSSIPPALAHLDSKMVDHILG------ESMHDFKPVAWEDIAGLESAKS 260
             :|.       .|:.|..||.|..:.||.:.:..:.|      .::|:..|:.
Human   524 LSDYIGEYSYLGTTLRQVSIEPMPSLLDVRQLITLYGIWPLGSAAVHEKAPLV------------ 576

  Fly   261 TFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVG 325
                                   :.:||.||.|.||.::..:|.::..|..|:::.|::..|:.|
Human   577 -----------------------KSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPG 618

  Fly   326 --DAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKR--SANENESTLRLKNEFLIHLDGAAS--NE 384
              ..:.::..:|.||...||::::|::.:....|:  :|.:.....|||.    ||.....  ..
Human   619 KNGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKK----HLPQILKLLKP 679

  Fly   385 EIRVLVIGATNRPQELD-EAVRRRFVRRLYVPLPTREAR----QKIIEKLIHQVKHNLDVRQVIE 444
            :.|:|::|.|.||.:.: ::..:.:.:.:.||.|...:|    ::|||:....:...|:|..
Human   680 DDRILIVGTTRRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSC--- 741

  Fly   445 LAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDC 509
            ||::|||::...:        :..::.:..||....:.|:  .:|..:|..|:..:: .|..|:.
Human   742 LAKVTDGFTQGHI--------VEVVKGVLTDQRIRRQIHK--PLTAVEFITAITSMN-PVYKEEE 795

  Fly   510 KQFEAW 515
            :.|:.|
Human   796 ESFKNW 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	34/142 (24%)
		AAA	286..416	CDD:278434	33/136 (24%)
		Vps4_C	<480..520	CDD:286426	8/36 (22%)
IQCA1	NP_001257514.1	SpoVK	<497..796	CDD:223540	69/351 (20%)
		AAA	579..712	CDD:278434	33/136 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900