DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fign and pex1

DIOPT Version :9

Sequence 1:	NP_001259995.1	Gene:	Fign / 33544	FlyBaseID:	FBgn0031519	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_001164306.1	Gene:	pex1 / 793906	ZFINID:	ZDB-GENE-070530-1	Length:	1237	Species:	Danio rerio

Alignment Length:	371	Identity:	113/371 - (30%)
Similarity:	181/371 - (48%)	Gaps:	49/371 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 REQLIMDELKKKN---RQATSEVDAVPTGMMNFRKKTLG--GKRTVSSNFVSPVAQNDNSTSSR- 217
            |.:::...:.||:   .|.|.::|:|......|..:.|.  .:|.:.:|    ...|....|.:
Zfish   709 RVEILKSLIVKKSFQVCQTTLDLDSVAKETEGFMARDLNLLLERAIHAN----TLHNSEDLSCKD 769

  Fly   218 -----SSSIPPAL--AHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDL 275
                 ....||:|  |.|.:..     |..|        |.|.||..|:...::.|::|.:.|.|
Zfish   770 FRQALQGFTPPSLWDAQLQAPS-----GAGM--------ERIGGLHEARQLLMDIILLPAKYPLL 821

  Fly   276 FTGV---RCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAV 337
            |:.:   :|  .||||:|.|||||||:|.::|.::...|.||....|.||::|.:|:.|:.:|..
Zfish   822 FSSLPLRQC--SGVLLYGAPGTGKTLLAGAVAKESGMNFISIKGPELLSKYIGASEQAVRDVFQR 884

  Fly   338 AAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEFLIHLDGAASNEEIR-VLVIGATNRPQELD 401
            |...:|.|:|.||.|||..:|..:....|.|:.|:.|..|||.   |.:. |.|:.|::||..:|
Zfish   885 AQQAKPCILFFDEFDSLAPRRGHDNTGVTDRVVNQLLTQLDGV---EGLTGVYVLAASSRPDLID 946

  Fly   402 EAVRR--RFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYA 464
            .|:.|  |..:.||.|.|.||||.:|:..|.|.|....|| .:.::|..|:.::|||:..|...|
Zfish   947 PALLRPGRLDKSLYCPPPDREARLEILRALTHSVPLAADV-DLDQIAGATELFTGADLKALLYNA 1010

  Fly   465 SMAPLR-SLTPDQMEVIETHQLPAVTMDDFK-QALRVISKSVSSED 508
            .:..:. ||.|:.:     |.|.:.:..|.. .:|..::.|..|:|
Zfish  1011 QLEAIHSSLGPNLL-----HDLGSGSDSDVSLSSLIFLNHSSGSDD 1051

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	54/138 (39%)
		AAA	286..416	CDD:278434	52/132 (39%)
		Vps4_C	<480..520	CDD:286426	7/30 (23%)
pex1	NP_001164306.1	PEX-2N	12..89	CDD:286362
		PEX-1N	101..171	CDD:286361
		SpoVK	559..1026	CDD:223540	106/344 (31%)
		P-loop_NTPase	559..686	CDD:304359
		AAA	833..962	CDD:278434	52/131 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000