Protein Alignment Fign and pex6

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_001332652.6
• Gene: pex6 / 792998
• ZFINID: ZDB-GENE-081104-252
• Length: 1071
• Species: Danio rerio
• Alignment Length: 550
• Identity: 140/550 - (25%)
• Similarity: 242/550 - (44%)
• Gaps: 120/550 - (21%)

  Fly    20 RSSSESIHFAALKDHHARL-----QACESMEKAMKERCQ---------KKITMSRRTKRGITHAG 70
            |:.|..:|...:|.....|     .|.|:..|::.||.:         :.:.:..:::.|.
Zfish   577 RAVSRRLHLHLIKVDCVTLCADTAAASEAKIKSVFERAELHHPCLLLLRNLQLLGQSRDGA---- 637

  Fly    71 YLFEMPHNSVFEPECRGFYESCQ-----QTEM-----ASSDLQAPALEVSSTYPVQQAVKSRPEG 125
                       |.:||.....||     .|.:     .||..:.|: :|.:.:..|.|::|..|.
Zfish   638 -----------ETDCRVAATLCQLIAAVHTSVVVVGSVSSQHELPS-DVMAAFVHQVAIESLSED 690

  Fly   126 QFPESRNNSTKKIDAQQYSSESSSQSGFGFRTAREQLIMDELKKKNRQATSEVDAVPTGMMNFRK 190
            |                            .||....|..|.|..|:           ..:....|
Zfish   691 Q----------------------------RRTVLSSLSEDLLLGKD-----------VNLGRIAK 716

  Fly   191 KTLG-------------GK----RTVSSNF---VSPVAQNDNSTSSRSSSIPPALAHLDSKMVDH 235
            :|.|             ||    |.|.:.|   ||...:.|...|..|.:.....|.||.....|
Zfish   717 QTAGFVLGDLCALLTNAGKAAHRRLVETYFPEAVSEQEEEDLCVSGVSVTSEDFSAALDVLQEAH 781

  Fly   236 ILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFT-GVRCPPRGVLLFGPPGTGKTLI 299
            ...........|:|:|:.||:..|...|:.|.:||..|:|.: |:|  ..|:||:|||||||||:
Zfish   782 SQAIGAPKIPAVSWQDVGGLQQVKKEILDTIQLPLEHPELLSLGLR--RSGLLLYGPPGTGKTLL 844

  Fly   300 AKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENE 364
            ||::|::....|.|:....|.:.:||.:|:.::.:|:.|.:..|.|||.||:|||...|..:.:.
Zfish   845 AKAVATECTMTFLSVKGPELINMYVGQSEENIRQVFSKARSAAPCIIFFDELDSLAPNRGHSGDS 909

  Fly   365 STL--RLKNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRR--RFVRRLYVPL-PTREARQK 424
            ..:  |:.::.|..|||..|:.:  |.||||||||..||:::.|  ||.:.:||.: ..||::.:
Zfish   910 GGVMDRVVSQLLAELDGLHSSGD--VFVIGATNRPDLLDQSLLRPGRFDKLVYVGINEDRESQLQ 972

  Fly   425 IIEKLIHQVKHNLDVRQVIELAELTDG----YSGADVDTLCRYASMAPLRSLTPDQMEVIETHQL 485
            :::.::.:.|    |...:.|:::.:.    .:|||:.:||..|.|..::.......|.::: :|
Zfish   973 VLKAILRKFK----VDASVCLSDIVESCPPRLTGADLYSLCSDAMMCAVKRKISRITEGVDS-EL 1032

  Fly   486 PAVTM--DDFKQALRVISKSVSSEDCKQFE 513
            .::|:  :||.:||..:..|||.:...:::
Zfish  1033 SSLTLCSEDFSEALSGLQPSVSEQQISRYQ 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	8/34 (24%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	69/189 (37%)
		AAA_lid_3	444..495	CDD:465537	13/56 (23%)
		Vps4_C	<480..520	CDD:462762	9/35 (26%)
pex6	XP_001332652.6	None