Protein Alignment Fign and vps4a

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001070077.1
• Gene: vps4a / 767670
• ZFINID: ZDB-GENE-060929-388
• Length: 440
• Species: Danio rerio
• Alignment Length: 315
• Identity: 131/315 - (41%)
• Similarity: 186/315 - (59%)
• Gaps: 33/315 - (10%)

  Fly   159 REQLIMDELKKKNRQATSEVDAVPTGMMNFRKKTLGGKRTVSSNFVSPVAQNDNSTSSRSSSIPP 223
            |.:.:.|.||.|::|                     ||:.|..     ...||.|.|......|.
Zfish    66 RAEKLKDYLKNKDKQ---------------------GKKPVKE-----TQSNDKSDSDSEGENPE 104

  Fly   224 ALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLL 288
                 ..|:.:|::|..:.:...|.|.|:||||.||....||:|:|::.|.||||.|.|.||:||
Zfish   105 -----KKKLQEHLMGAIVMEKPNVRWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILL 164

  Fly   289 FGPPGTGKTLIAKSIASQA-KAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVD 352
            ||||||||:.:||::|::| .:.|||::.|.|.|||:|::|||||.||.:|..|:|:||||||||
Zfish   165 FGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFDLARQHKPSIIFIDEVD 229

  Fly   353 SLLSKRSANENESTLRLKNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRRRFVRRLYVPLP 417
            ||...|:.||:|:..|:|.|||:.:.|..:|.: .:||:||||.|..||.|:||||.:|:|:|||
Zfish   230 SLCGSRNENESEAARRIKTEFLVQMQGVGNNND-GILVLGATNIPWVLDAAIRRRFEKRIYIPLP 293

  Fly   418 TREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSL 472
            ...||..:....:....|:|....:.:||..||||||||:..:.|.|.|.|:|.:
Zfish   294 EEPARSAMFRLHLGNTPHSLTEADLRQLARKTDGYSGADISIIVRDALMQPVRKV 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	94/185 (51%)
		AAA_lid_3	444..495	CDD:465537	15/29 (52%)
		Vps4_C	<480..520	CDD:462762
vps4a	NP_001070077.1	MIT_VPS4	4..79	CDD:239141	5/12 (42%)
		RecA-like_VPS4	120..290	CDD:410929	91/170 (54%)
		AAA_lid_3	317..358	CDD:465537	15/32 (47%)
		Vps4_C	373..>403	CDD:462762