DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fign and spata5l1

DIOPT Version :9

Sequence 1:	NP_001259995.1	Gene:	Fign / 33544	FlyBaseID:	FBgn0031519	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_001070056.2	Gene:	spata5l1 / 767648	ZFINID:	ZDB-GENE-060929-204	Length:	748	Species:	Danio rerio

Alignment Length:	327	Identity:	112/327 - (34%)
Similarity:	171/327 - (52%)	Gaps:	52/327 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 ALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFT--GVRCPPRGV 286
            ||.|:....:...:|.:  ||||:.||.|.|||..|....::|..|:|.|:.|.  || ..||||
Zfish   428 ALRHVQPSCLRSSIGAT--DFKPIGWEQIGGLEDVKLKLKQSIEWPMRFPEAFVRLGV-SRPRGV 489

  Fly   287 LLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEV 351
            ||:||||..||.:.|:.||.:...|||::.:.|.|.:|||:||.:..|||.|.|..|:|:|:|||
Zfish   490 LLYGPPGCAKTTLVKAAASSSHCSFFSLSGAELFSPYVGDSEKTLAQLFAQARACAPSIVFLDEV 554

  Fly   352 DSLLSKR---SANENESTLRLKNEFLIHLDG-------------------AASNEEIR------- 387
            ||::..|   |::.:....::.:..|..|||                   ....|::|
Zfish   555 DSMVGSREDGSSSSHSVQSQVLSVLLTELDGVGVRTLERRSTCRKIALLEGGDQEDVRLHQMELQ 619

  Fly   388 ------VLVIGATNRPQELDEAVRR--RFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIE 444
                  ||::.|||||:.||.|:.|  |..:.:|||.|..:||..::......|..:.|| .:.:
Zfish   620 EVCNKDVLIVAATNRPEALDSALLRPGRLDQIIYVPPPDLQARLAVLRICTKSVPLHQDV-CLED 683

  Fly   445 LAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDC 509
            ||..|:.:||||::.||:.|::..||.   |.:.|      ..|....|.:||:::|.|:|:|..
Zfish   684 LAAQTELFSGADLENLCKEAALLALRE---DGLAV------SCVRQKYFLKALQMLSPSLSAEQL 739

  Fly   510 KQ 511
            :|
Zfish   740 QQ 741

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	61/172 (35%)
		AAA	286..416	CDD:278434	57/166 (34%)
		Vps4_C	<480..520	CDD:286426	9/32 (28%)
spata5l1	NP_001070056.2	CDC48	13..740	CDD:273521	111/324 (34%)
		AAA	224..357	CDD:278434
		AAA	489..655	CDD:278434	56/165 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900