Protein Alignment Fign and Iqca1

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001355651.1
• Gene: Iqca1 / 74918
• MGIID: 1922168
• Length: 838
• Species: Mus musculus
• Alignment Length: 514
• Identity: 100/514 - (19%)
• Similarity: 205/514 - (39%)
• Gaps: 109/514 - (21%)

  Fly    45 EKAMKERCQKKITMSRRTKRGITHAGYLFEMPHNSVFEPECRGFYESCQQTEMASSDLQAPALEV 109
            :|..||:.:||:::..:..:                         :..::.:|:.|.......|.
Mouse   368 KKEKKEKKEKKVSLKEKAMK-------------------------DEDEEWKMSPSLFLQLMEEG 407

  Fly   110 SSTYPVQQAVKSRPEG-QFPESRNNSTKKIDAQQYSSESSSQSGFGFRTAREQLIMDELKKKNRQ 173
            :|.|  :....::.|. .||:.       .|.:....|...:.....|...::|:..|||.....
Mouse   408 NSLY--KDIWLNKDESWNFPQD-------YDPELIKEEKRKELEMEIRVQVDELMRQELKNLKLA 463

  Fly   174 ATSEVDAVP---------------TGMMNFRKKTLGGKRTVSSNFVSPVAQNDNSTSSRSSSIPP 223
            ...|::..|               .|....::|.|...||:.|.:...|.:.            .
Mouse   464 VNREMEIPPRQKKGKKKNKGRKGRRGKRGKKEKDLTADRTIESLYQELVEKG------------L 516

  Fly   224 ALAHLDSKMVDHI-----LGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCP- 282
            .:..|...:.|:|     ||.::   :.||.|.:..|...:.......|:||...::..  |.|
Mouse   517 LIQALKVNLSDYIGEYSYLGTTL---RQVAIEPMPSLLDVRQLITLYGILPLGSAEVHE--RAPL 576

  Fly   283 PRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDA--EKLVKTLFAVAAAHQPAI 345
            .:.:||.||.|.||.::..:|.::..|..|:::..::..|:.|..  :.::..:|.||...||::
Mouse   577 VKSLLLAGPSGVGKKMLVHAICTETGANLFNLSALNIAGKYPGKTGLQMMIHLVFKVARQLQPSV 641

  Fly   346 IFIDEVDSLLSKR--SANENESTLRLKNEF--LIHLDGAASNEEIRVLVIGATNRPQELD-EAVR 405
            ::|.:.:....|:  .|.:.....|||...  |:.|    ...:.|:|::|.|:||.:.: :...
Mouse   642 VWIQDTEKTFYKKVPQAEKRFEPKRLKRYLPKLLKL----LKPDDRILIVGTTHRPFDAELQPFC 702

  Fly   406 RRFVRRLYVPLPTREARQKIIEKLI----HQVKHNLDVRQVIELAELTDGYSGA-------DVDT 459
            |.:.:.:.||.|...:|..:.:::|    .::.::|::..   |:::|||::..       ||.|
Mouse   703 RVYQKIILVPRPDYASRYVLWKEIILRNGGKLTNSLNISC---LSKVTDGFTQGQIVQVIKDVLT 764

  Fly   460 LCRYASMAPLRSLTPDQMEVIETHQLPAVTMDD--FKQ--------ALRVISKSVSSED 508
            ..|....|. :.||..:...:.|:..|....::  ||.        ..||:|.:|.:::
Mouse   765 ERRLRQQAH-KPLTAIEFITMMTNMNPVYREEEESFKNWYAKTPLGKKRVLSLTVGNKE 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	1/4 (25%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	45/197 (23%)
		AAA_lid_3	444..495	CDD:465537	14/59 (24%)
		Vps4_C	<480..520	CDD:462762	8/39 (21%)
Iqca1	NP_001355651.1	P-loop containing Nucleoside Triphosphate Hydrolases	552..711	CDD:476819	37/164 (23%)