Protein Alignment Fign and Katnal2

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001355584.1
• Gene: Katnal2 / 71206
• MGIID: 1924234
• Length: 539
• Species: Mus musculus
• Alignment Length: 557
• Identity: 167/557 - (29%)
• Similarity: 279/557 - (50%)
• Gaps: 90/557 - (16%)

  Fly    26 IHFAALKDHHARLQACESMEKAMKERCQKKITMSRRTKRGITHAGYLFEMPHNSVFEPECR-GF- 88
            :.:..||..|   ||.|:.|...:.|.:..:.:   ....:|..||   |......|.|.: |.
Mouse     3 LSYQTLKLTH---QAREAYEMRTEARRKNLLIL---ILHYLTQEGY---MDAAKALEEETKLGLR 58

  Fly    89 -YESCQQTEMASSDLQAPALEVSSTY----------------PVQQAVKSRPEGQFPESRNNSTK 136
             :|.|...     ||:...:|..|.|                ||:..:.||..|:.....|:|.:
Mouse    59 RFEVCDNV-----DLETILMEYESYYFVKFQKYPKVVKKAPDPVENNLPSRSGGKNKRLTNDSCQ 118

  Fly   137 ---KIDAQQYSSESSSQSGFGFRTAREQLIMDELKKKNRQAT-SEVDAVPTGM------------ 185
               ||..|:...::|:     .:|...:.:.:.||:.....| ::.::...|:
Mouse   119 NLPKICHQKSRPKTSA-----VKTGDTKSVKEHLKQVKESVTDTQAESTDFGLNISKIHKDQPEE 178

  Fly   186 ---------MNFRKKTLGGKRTVSSNFVSPVAQNDNSTSSRSSSIPPALAHLDSKM--VDHILGE 239
                     ::||.......:..:|.|.....:.:...|.|......|...::|:|  :..::..
Mouse   179 KAQPRRGQIIDFRGLLSDAIKGATSEFALNTFECNPDPSERLLKPLSAFIGMNSEMRELAAVVSR 243

  Fly   240 SMHDFKP-VAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSI 303
            .::...| :.|.||.||::||....||::.|:|.|.||||:..|.:|:||:|||||||||:||::
Mouse   244 DIYLHNPNIKWNDIIGLDAAKQLVKEAVVYPIRYPQLFTGILSPWKGLLLYGPPGTGKTLLAKAV 308

  Fly   304 ASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRS---ANENES 365
            |::.|..||:|:.|::.|||.||:||||:.||.:|..|.|:.||:||::|::|:|.   ..|:|.
Mouse   309 ATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGMVPGGEHEG 373

  Fly   366 TLRLKNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLI 430
            :||:|.|.|:.:||.|.:|:: |.|:.|:|.|.|||.|:.||..:|:.|.||::||||.:|...:
Mouse   374 SLRMKTELLVQMDGLARSEDL-VFVLAASNLPWELDCAMLRRLEKRILVDLPSQEARQAMIYHWL 437

  Fly   431 HQV--KHNLDVRQVIE---LAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQ-----L 485
            ..|  .|.|::...:|   |::.|:||||:|:..:||.|:|.|:|.:    ..|:|.:|     |
Mouse   438 PPVSKNHALELHTQLEYSVLSQETEGYSGSDIKLVCREAAMRPVRKI----FSVLENNQSESNNL 498

  Fly   486 PAVTMD-----DFKQALRVISKSVSSEDCKQFEAWNE 517
            |.:.:|     ||...| ..:|..:....:::.||.|
Mouse   499 PGIQLDTVTTQDFLDVL-AHTKPSAKNLTERYLAWQE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	7/23 (30%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	84/190 (44%)
		AAA_lid_3	444..495	CDD:465537	22/63 (35%)
		Vps4_C	<480..520	CDD:462762	12/48 (25%)
Katnal2	NP_001355584.1	LisH	25..55	CDD:128913	7/35 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..121		7/27 (26%)
		RecA-like_VPS4-like	257..421	CDD:410917	79/164 (48%)
		AAA_lid_3	457..495	CDD:465537	16/41 (39%)