DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fign and Spata5l1

DIOPT Version :9

Sequence 1:	NP_001259995.1	Gene:	Fign / 33544	FlyBaseID:	FBgn0031519	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_001103117.1	Gene:	Spata5l1 / 691729	RGDID:	1595990	Length:	747	Species:	Rattus norvegicus

Alignment Length:	501	Identity:	132/501 - (26%)
Similarity:	221/501 - (44%)	Gaps:	107/501 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 EPECRGFYESCQQTEMASSDLQAPAL----EVSSTYPVQQAVKSRPEGQFPESRNNSTKKIDAQQ 142
            |...|..::..|  |:||   :.|:|    ||.:..|.:...:..||           .::.||.
  Rat   272 EENVRRVFQRAQ--ELAS---RGPSLLFLDEVDALCPRRGGPQRAPE-----------SRVVAQV 320

  Fly   143 YSSESSSQSGFGFRTAREQLIM------DE----LKKKNRQATSEVDAVPTGMMNFRKKTLG--- 194
            .:...      |....||.:::      ||    |::..|.....:...||  :..|:..||
  Rat   321 LTLLD------GIHGDREVVVVGATNRPDELDPALRRPGRFDREVIIGTPT--LKQREAILGVIT 377

  Fly   195 GKRTVSSNF---------VSPVA-------------------QNDNSTSSRSSSIPPALAHLDSK 231
            .|..:||:.         |..|.                   :|.|:.....:....|...:...
  Rat   378 SKMPISSHIDLGLLAEMTVGYVGADLTALCREAATCALLKNEKNQNNPKIEETDFLEAFKKVQPS 442

  Fly   232 MVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGV-RCPPRGVLLFGPPGTG 295
            .....:|  :.|.:||.||.|.|||..|....:.:..||:.|..|..: ...|:|:||:||||..
  Rat   443 SFRSSIG--LTDIRPVGWEQIGGLEDVKLKLKQCVEWPLKFPQEFARMGLTQPKGLLLYGPPGCA 505

  Fly   296 KTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSA 360
            ||.:.:::|:.....|.|:..:.|.|.:|||:||::..:|..|.|:.||::|:||:||:|..||.
  Rat   506 KTTLVRALATSCHCSFVSVCGADLFSPFVGDSEKVLSQVFRQARANTPALVFLDEIDSVLGSRSV 570

  Fly   361 NEN--ESTLRLKNEFLIHLDGA-----------ASNEEIR------VLVIGATNRPQELDEAVRR 406
            ..:  ::..|:.:..|..|||.           ||.:|.:      |:::.|||||..||:|:.|
  Rat   571 GSSGCDARERVLSVLLNELDGVGVRTVERRGSKASQQECQEILSRSVMIVVATNRPDVLDDALLR 635

  Fly   407 --RFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPL 469
              |..:.:|||.|.||.|..|::...:.:...|:| .:..||..|..:||||:..||:.|::..|
  Rat   636 PGRLDKMVYVPPPDREGRLSILKVCTNNMPIGLNV-SLENLAAETCYFSGADLRNLCKEAALFAL 699

  Fly   470 RSLTPDQMEVIETHQLPAVTMDD--FKQALRVISKSVSSEDCKQFE 513
                       :.:.|.|.|::.  |.:||:.:..|::.:|...:|
  Rat   700 -----------QENGLEATTVEQEHFTEALKTVKPSLTLKDLTFYE 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	55/156 (35%)
		AAA	286..416	CDD:278434	52/150 (35%)
		Vps4_C	<480..520	CDD:286426	9/36 (25%)
Spata5l1	NP_001103117.1	CDC48	14..738	CDD:273521	132/501 (26%)
		AAA	230..362	CDD:278434	22/111 (20%)
		AAA	496..646	CDD:278434	51/149 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900