Protein Alignment Fign and ATAD2B

DIOPT Version :9

• Sequence 1: NP_001259995.1
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_011531220.1
• Gene: ATAD2B / 54454
• HGNCID: 29230
• Length: 1511
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 144/569 - (25%)
• Similarity: 234/569 - (41%)
• Gaps: 132/569 - (23%)

  Fly    30 ALKDHHARLQ-------ACESMEKAMKERCQKKITMSRRTKRGITHAGYLFEMPHNSVFEPECR- 86
            :|:.|..|.:       :|.:.:..:::.|:     ||:.:....:...||:...||..|...:
Human   140 SLRSHPLRGEKKGDGDLSCINGDMEVRKSCR-----SRKNRFESVNQSLLFDQLVNSTAEAVLQE 199

  Fly    87 ------------GFYESCQ---QTEMASSDL------QAPALEVSSTYPVQQAVKSRPEGQFPES 130
                        |..|..:   .||..:.|:      :..:|..:| |.:|...:...||   |.
Human   200 MDNINIRRNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNS-YGIQNHHEVSTEG---EE 260

  Fly   131 RNNSTKKIDAQQYSSESSSQSG---------------FGFR----TAREQL--IMDELKKKNRQA 174
            ...::|.:..::.|.||..:.|               :..|    ..|.|.  |:...:||....
Human   261 EARTSKLLPLEKISIESQEEDGDIEVEEAEGEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENT 325

  Fly   175 TSEVDAVPTGMMNFRKKTLGGKRTVSSNFVSPVAQNDNSTSSRSSS------------------- 220
            ..::...|....:.|:|    |..:.|   |....:|.....|..|
Human   326 LFDIHRSPARRSHIRRK----KHAIHS---SDTTSSDEERFERRKSKSMARARNRCLPMNFRAED 383

  Fly   221 -----------IPPALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPD 274
                       :..:||.:|...:|          |.|.::.|.||........|.::.||..|:
Human   384 LASGILRERVKVGASLADVDPMNID----------KSVRFDSIGGLSHHIHALKEMVVFPLLYPE 438

  Fly   275 LFTGVRC-PPRGVLLFGPPGTGKTLIAKSIASQA-----KAKFFSINPSSLTSKWVGDAEKLVKT 333
            :|...:. ||||.|.:|||||||||:|:::|::.     |..||....:...|||||::|:.::.
Human   439 IFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRL 503

  Fly   334 LFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEFLIHLDGAASNEEIRVLVIGATNRPQ 398
            ||..|...:|:|||.||:|.|...||:.:::....:.:..|..:||..:..||  :|||||||..
Human   504 LFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEI--VVIGATNRLD 566

  Fly   399 ELDEAVRR--RFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVI--ELAELTDGYSGADVDT 459
            .:|.|:||  ||.|.....||.::||:.|::  ||....|..:....  ||||...||.|||:..
Human   567 SIDPALRRPGRFDREFLFNLPDQKARKHILQ--IHTRDWNPKLSDAFLGELAEKCVGYCGADIKA 629

  Fly   460 LCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSED 508
            ||..|::..||            .:.|.:.....|..|.|.|..:|::|
Human   630 LCTEAALIALR------------RRYPQIYASSHKLQLDVSSIVLSAQD 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	58/142 (41%)
		AAA	286..416	CDD:278434	53/136 (39%)
		Vps4_C	<480..520	CDD:286426	7/29 (24%)
ATAD2B	XP_011531220.1	AAA	447..588	CDD:214640	58/142 (41%)
		AAA	452..586	CDD:278434	53/135 (39%)
		COG5076	866..>1100	CDD:227408
		Bromo_AAA	974..1085	CDD:99957

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810