DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fign and katnal1

DIOPT Version :9

Sequence 1:	NP_001259995.1	Gene:	Fign / 33544	FlyBaseID:	FBgn0031519	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_001007432.1	Gene:	katnal1 / 492790	ZFINID:	ZDB-GENE-041114-141	Length:	488	Species:	Danio rerio

Alignment Length:	306	Identity:	125/306 - (40%)
Similarity:	204/306 - (66%)	Gaps:	18/306 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 DSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPG 293
            ||.:||.:..:.:.....:.|:|||.||.||....||:::|:..||.|.|:|.|.:|||:.||||
Zfish   185 DSDLVDALERDIVSRNPNIHWDDIADLEDAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPG 249

  Fly   294 TGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKR 358
            ||||::||::|::....||:::.|:||||:.|::||||:.||.:|..:.|..|||||:||:..:|
Zfish   250 TGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICGRR 314

  Fly   359 -SANENESTLRLKNEFLIHLDGAASNEEIR-----VLVIGATNRPQELDEAVRRRFVRRLYVPLP 417
             :::|:|::.|:|:|.|:.:||....:|..     |:|:.|||.|.::|||:|||..:|:|:|||
Zfish   315 GTSDEHEASRRVKSELLVQMDGVGGAQESEDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLP 379

  Fly   418 TREARQKIIEKLIHQVKHNLDVRQVIEL---AELTDGYSGADVDTLCRYASMAPLR----SLTPD 475
            |.:.|.::::..:.:|    ||...::|   ||..:||||||:..:||.|||..:|    .|:|:
Zfish   380 TAKGRAELLKINLREV----DVASDVDLTVFAEKIEGYSGADITNVCRDASMMAMRRRIQGLSPE 440

  Fly   476 QMEVIETHQLP-AVTMDDFKQALRVISKSVSSEDCKQFEAWNEIYG 520
            ::..:...:|. .|||:||:.||:.||||||:.|.:::|:|...:|
Zfish   441 EIRALSKDELQMPVTMEDFELALKKISKSVSAADLEKYESWMSEFG 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	64/141 (45%)
		AAA	286..416	CDD:278434	60/135 (44%)
		Vps4_C	<480..520	CDD:286426	17/40 (43%)
katnal1	NP_001007432.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	84..184
		AAA	238..380	CDD:214640	64/141 (45%)
		AAA	242..378	CDD:278434	60/135 (44%)
		Vps4_C	<448..486	CDD:286426	17/37 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593583
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840