Protein Alignment Fign and NSF

DIOPT Version :9

• Sequence 1: NP_001259995.1
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_006169.2
• Gene: NSF / 4905
• HGNCID: 8016
• Length: 744
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 113/414 - (27%)
• Similarity: 181/414 - (43%)
• Gaps: 82/414 - (19%)

  Fly   129 ESRNNSTKKIDA---QQYSSESSS---QSGFGFRTAREQLIMDELKK------KNRQATSEVDAV 181
            :|....|.|:.|   ||:::::.|   |..|.|......|::.:::.      |...||.:...:
Human   108 DSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKI 172

  Fly   182 PTGMMNFRKKTLGGKRTVSS-NFVSPVAQNDNSTSSRSSSIPPALAHLDSKMVDHILGESMHDFK 245
            ..|::....:....|...|| |.:......:|    |.|.|.|
Human   173 EVGLVVGNSQVAFEKAENSSLNLIGKAKTKEN----RQSIINP---------------------- 211

  Fly   246 PVAWE----DIAGLESAKS-TFLEAIIMPLRRPDLFTGVRCP-PRGVLLFGPPGTGKTLIAKSIA 304
              .|.    .|.||:...| .|..|....:..|::...:.|. .:|:||:||||.||||:|:.|.
Human   212 --DWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIG 274

  Fly   305 SQAKAKFFS-INPSSLTSKWVGDAEKLVKTLFAVAAAHQPA--------IIFIDEVDSLLSKRSA 360
            ....|:... :|...:.:|:||::|..::.|||.|...|..        ||..||:|::..:|.:
Human   275 KMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGS 339

  Fly   361 NENESTLR--LKNEFLIHLDGAASNEEI-RVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTRE 420
            ....:.:.  :.|:.|..:||.   |:: .:||||.||||..:|||:.|  |...::.:.||..:
Human   340 MAGSTGVHDTVVNQLLSKIDGV---EQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEK 401

  Fly   421 ARQKIIEKLIHQVK---HNL---DVRQVIELAELTDGYSGADVDTLCRYA-SMAPLRSLTPD--- 475
            .|.:|:.  ||..:   |.|   || .:.|||..|..:|||:::.|.|.| |.|..|.:...
Human   402 GRLQILH--IHTARMRGHQLLSADV-DIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKV 463

  Fly   476 --QMEVIETHQLPAVTMDDFKQAL 497
              .||..|:.|   ||..||..:|
Human   464 EVDMEKAESLQ---VTRGDFLASL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	49/150 (33%)
		AAA	286..416	CDD:278434	47/143 (33%)
		Vps4_C	<480..520	CDD:286426	7/18 (39%)
NSF	NP_006169.2	CDC48_N	6..83	CDD:215012
		CDC48_2	111..>159	CDD:308534	10/47 (21%)
		SpoVK	<142..490	CDD:223540	103/380 (27%)
		AAA	538..670	CDD:214640

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900