Protein Alignment Fign and Pex1

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Alignment Length: 561
• Identity: 139/561 - (24%)
• Similarity: 226/561 - (40%)
• Gaps: 121/561 - (21%)

  Fly    37 RLQACESMEKAMKERCQKKITMSRRTKRGITHAGYL-----------FEMPHNS--------VFE 82
            |:..|.|.:.::..:|...:..:..|.:.:.....|           ||..|.|        ..:
  Fly   463 RMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGSRSKGRKTESIQ 527

  Fly    83 PECRGFYESCQQTEMASSDLQAPALEVSSTYPV---QQAVKSRPEGQF-------------PESR 131
            .:.|..:.||.|        .|||:.|.....|   ....:|..:|::             ..:.
  Fly   528 KDLRNIFTSCLQ--------HAPAIVVLENLDVLAHAAGEQSSQDGEYYNRMADTVYQLIVQYTT 584

  Fly   132 NNSTKKI----DAQQYSSESSSQSG-FGFRT---------AREQLIMDELKKKNRQATSEVD-AV 181
            ||:...|    :.|..:...||..| ..|:|         |..::|:.||       .|.:: |.
  Fly   585 NNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADREIILREL-------CSHINVAK 642

  Fly   182 PTGMMNFRKKTLGGKRTVSSNFV-------------SPVAQNDNSTSSRSSSIPPALAHLDSKMV 233
            ...::.|...|.|.::.....||             .|:..||....|        |.|.:|..:
  Fly   643 DLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIES--------LEHTNSYCL 699

  Fly   234 DHILGESM----HDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPR---GVLLFGP 291
            ..|.....    .|...:..|::.||||......|.::.|.|.|.:|..  .|.|   ||||:||
  Fly   700 QGIQSNQRTGNDADANEMRVEELPGLESVVGVLEEVLMWPSRYPTIFNA--SPLRNQAGVLLYGP 762

  Fly   292 PGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLS 356
            ||||||.:...:|:....:..|:....|.:|::|.:|:.|:.||..|.:.:|.::|.||.|||..
  Fly   763 PGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEFDSLAP 827

  Fly   357 KRSANENESTLRLKNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTR 419
            ||..:....|.|:.|:.|..|||....:  .|.||.||:||:.||.|:.|  |..|.:..|||..
  Fly   828 KRGHDSTGVTDRVVNQLLTELDGVEGLQ--GVTVIAATSRPELLDPALLRSGRIDRLVECPLPDA 890

  Fly   420 EARQKIIEKLIHQVKHNLDVRQVIE---LAELTDGYSGADVDTLCRYASMAPL------------ 469
            .||.:|.|.|    ...|.:.:.::   .|..|..|:|||:.::...|:||.:
  Fly   891 PARVRIFEAL----SSTLSLDECVDFDWFAGKTANYTGADIQSILTSANMAAVKEALAQFGHEKL 951

  Fly   470 -RSLTPDQMEVIETHQL--PAVTMDDFKQALRVISKSVSSE 507
             :.::..|..:||:.|.  |:::..|..:..|..::..:.|
  Fly   952 AKKISLKQKHLIESFQTTRPSLSASDVAKYHRTYARFTNKE 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	3/12 (25%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	66/193 (34%)
		AAA_lid_3	444..495	CDD:465537	15/68 (22%)
		Vps4_C	<480..520	CDD:462762	7/30 (23%)
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	137/550 (25%)
		RecA-like_PEX1_r2	728..885	CDD:410934	58/160 (36%)