Protein Alignment Fign and nvl

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_998649.1
• Gene: nvl / 406805
• ZFINID: ZDB-GENE-040426-2871
• Length: 796
• Species: Danio rerio
• Alignment Length: 539
• Identity: 147/539 - (27%)
• Similarity: 231/539 - (42%)
• Gaps: 138/539 - (25%)

  Fly    14 LICQQTRSSSESIHFAALKDHHARLQACESMEKAMKERCQKKITMSRRTKRGITHAGYLFEMPHN 78
            |||.:  |.||   |:||::.|                      :::|.:|
Zfish    64 LICSE--SDSE---FSALENKH----------------------LAKRARR-------------- 87

  Fly    79 SVFEPECRGFYESCQQTEMASSDLQAPALEVSSTYPVQQAVKSRPEGQFPESRNNSTKKI---DA 140
               .||                |.....:..|||    .:....||.:.....|:|...:   .|
Zfish    88 ---SPE----------------DGDGSHVTASST----DSEDDIPEHEHTNHMNSSLTSLYQRGA 129

  Fly   141 QQYSSESSSQSGF---------GFRTAREQLIMDELKKKNRQATSEVDAVPTGMMNFRKKTLGGK 196
            ...||.|:.|...         |.| .:|.:::|..::::...|::.|   :..:...||::..|
Zfish   130 ANASSSSTIQRSLSDDWIIDKTGDR-GQESILIDLCEEESSSTTNQRD---SSRLEKEKKSVKQK 190

  Fly   197 RTVSSNFVSPVAQNDNSTSSRSSSIPPALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKST 261
            |...:..     :.|:.|   |:.:|..    .||:....|     .|..|.:||..|.:..
Zfish   191 RQKKNKL-----EEDSET---SAGVPAK----KSKVKGFEL-----QFSSVKFEDFGGSDET--- 235

  Fly   262 FLEAI---IMPLRRPDLF--TGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTS 321
             ||.:   ::.:|.|:::  .|| .||||.||.||||.||||:|:::|.:.......|:...|.|
Zfish   236 -LEEVCKLLIHMRHPEVYQRLGV-VPPRGFLLHGPPGCGKTLLAQAVAGETALPLLKISAPELVS 298

  Fly   322 KWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEFLIHLDGAASN-EE 385
            ...|::|:.::.||..|.:..|.|:||||:|::..||.....:...|:..:.|..:|...|. |.
Zfish   299 GVSGESEQKLRELFEQAISSAPCILFIDEIDAITPKRETASKDMERRIVAQLLTCMDDLNSMLEP 363

  Fly   386 IRVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTREARQKIIEKLIHQVK--HNLDVRQVIELA 446
            .:||||||||||..||.|:||  ||.|.:.:.:|...||.||::.|..:::  .:.|.|   .||
Zfish   364 AQVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEGARMKILKTLCRKIRLPDDFDFR---HLA 425

  Fly   447 ELTDGYSGADVDTLCRYASMAP-----LRSLTPDQ----------MEVIET------HQLPA--V 488
            .||.||.|||:..|||.|:|..     |...|.||          ::::::      .||.|  |
Zfish   426 RLTPGYVGADLMALCREAAMNAVNRILLEPTTEDQITPTLALARLLDLLKSSVSLSEDQLAALCV 490

  Fly   489 TMDDFKQALRVISKSVSSE 507
            .|.||..:|..:..|...|
Zfish   491 LMSDFSSSLVRVQPSAKRE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	10/35 (29%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	70/192 (36%)
		AAA_lid_3	444..495	CDD:465537	25/73 (34%)
		Vps4_C	<480..520	CDD:462762	10/36 (28%)
nvl	NP_998649.1	Nucleolin_bd	2..71	CDD:465247	4/8 (50%)
		CDC48	<218..796	CDD:273521	104/305 (34%)