DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fign and CG14183

DIOPT Version :9

Sequence 1:	NP_001259995.1	Gene:	Fign / 33544	FlyBaseID:	FBgn0031519	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_649172.3	Gene:	CG14183 / 40192	FlyBaseID:	FBgn0036931	Length:	872	Species:	Drosophila melanogaster

Alignment Length:	517	Identity:	99/517 - (19%)
Similarity:	182/517 - (35%)	Gaps:	164/517 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLICQQTRSSSE--------SIHFAALKDHHARLQACESMEKAMKERCQKKITMSRRTKR---- 64
            :|::..:|.:..|        .:..|.||    :|:..|..||..|:...|::.|....:|
  Fly   373 VLVVIDETMTPMEFQESLGKKPLSKAELK----KLRDKEKKEKRKKKEKLKQLKMKEAKRRKKLR 433

  Fly    65 --GITHAGYLFEMPHNSVFEPECRGFYESCQQTEMASSDLQAPALEVSSTYPVQQAVKS-----R 122
              |:...||                        |:.:|    .|:|     .:::.:|.     |
  Fly   434 DAGVIDIGY------------------------ELTAS----KAIE-----NIEETMKKYSKDWR 465

  Fly   123 PEGQFPESRNNSTKK-IDAQQYSSESSSQSGF--GFRTAREQLIMDELKKKNRQATSEVDA-VPT 183
            ...::....::..|: :..:|.:.......|.  .:.....:|:.:.|.|.|.:....:.. .|.
  Fly   466 NVDEYLNKNHDPIKEWVTEEQLAKIHQEVRGLVDEYMRVEYELLREALAKDNDEKYKALKVKYPK 530

  Fly   184 GMMNFRK---KTLGGKRTVSS--------------------------NFVSPVAQNDNSTSSRSS 219
            .....||   |.:.|.||:.|                          |||:...::::..::
  Fly   531 KKKEKRKKKPKDMTGDRTLESLYNELKDAGIIEEIGHRDFDEFITDFNFVADDTRDEDGLTT--- 592

  Fly   220 SIPPALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPR 284
                             ||.:..|.|.|..|.:.|:..        ..:|            .|:
  Fly   593 -----------------LGPAKGDIKMVIQESMLGMGE--------FDVP------------KPK 620

  Fly   285 GVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFID 349
            .:||.||..:||.|:.:.|||:..|.|.:::|.: |.|:..|.:..:..:..||.|.||.|::|:
  Fly   621 SLLLIGPLNSGKRLLCEIIASELDAVFMNLSPEN-TYKYAKDLKYFLHVILKVAKAFQPTIMYIE 684

  Fly   350 EVDSLLSKRSANEN-ESTLRLKNEFLIH--LDGAASNEEIRVLVIGATNRPQELDEAVRRRFVRR 411
            |...|..|:...|. |...||....|..  |.....|:  :::::|.:|.|...:..::|.|.:.
  Fly   685 EAHRLFWKKVPPEAVEINPRLLGTSLASKILKPLKKND--KIVLVGTSNMPWAANGGIKRAFQKV 747

  Fly   412 LYVP-------------LPTREARQKIIEKLIHQVKHNLDVRQVI--ELAELTDGYSGADVD 458
            |.:|             |.|..|..              |:::..  .||.:...|:..|:|
  Fly   748 LLIPKCDYGTSFLLWLELMTENAPD--------------DMKEYAYSALARVLQAYNSGDID 795

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	42/151 (28%)
		AAA	286..416	CDD:278434	40/145 (28%)
		Vps4_C	<480..520	CDD:286426
CG14183	NP_649172.3	AAA	622..751	CDD:278434	39/131 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900