Protein Alignment Fign and FIGNL2

DIOPT Version :9

• Sequence 1: NP_001259995.1
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_016874787.1
• Gene: FIGNL2 / 401720
• HGNCID: 13287
• Length: 767
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 127/461 - (27%)
• Similarity: 195/461 - (42%)
• Gaps: 79/461 - (17%)

  Fly    98 ASSDLQAPALEVSSTYPV------------QQAVKSRPEGQFPESRNNSTKK--IDAQQY-SSES 147
            |.:.|.|||...:..:|.            ::|....|||::.:......|.  .|...| ::::
Human   351 APTPLPAPAPPTAYGFPTAAPGAESGLSLKRKAADEGPEGRYRKYAYEPAKAPVADGASYPAADN 415

  Fly   148 SSQSGFGFRTAREQLIMDELKKKNRQATSEVDAVPTGMMNFRKKTLGG---KRTVSSNFVSPVAQ 209
            ....|.|||                       |.|.|.........||   .:.:.|....|..:
Human   416 GECRGNGFR-----------------------AKPPGAAEEASGKYGGGVPLKVLGSPVYGPQLE 457

  Fly   210 NDNSTSSRSSS----------------IPPALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESA 258
            .......|:.:                .|.||..:.|||||  .|      .||.|.|:||..:.
Human   458 PFEKFPERAPAPRGGFAVPSGETPKGVDPGALELVTSKMVD--CG------PPVQWADVAGQGAL 514

  Fly   259 KSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKW 323
            |:...|.::.||.||..:.|...|||.||||||.|.||.|:.:.:|:|..|....:..::|.:..
Human   515 KAALEEELVWPLLRPPAYPGSLRPPRTVLLFGPRGAGKALLGRCLATQLGATLLRLRGATLAAPG 579

  Fly   324 VGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEFLIHLDGAASNEEIRV 388
            ..:..:|::..||.|....|:::.|.|:::||..|........ .|:...|..|||........|
Human   580 AAEGARLLQAAFAAARCRPPSVLLISELEALLPARDDGAAAGG-ALQVPLLACLDGGCGAGADGV 643

  Fly   389 LVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYS 453
            ||:|.|:||..||||.||||..|.||.||...||.:|:::.:.|....|..|::..|.:.|.|:|
Human   644 LVVGTTSRPAALDEATRRRFSLRFYVALPDSPARGQILQRALAQQGCALSERELAALVQGTQGFS 708

  Fly   454 GADVDTLCRYASM-APLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDCKQFEAWNE 517
            |.::..||:.|:. |.|..|           |.| ::..|.:.||..:....|:::...|..|::
Human   709 GGELGQLCQQAAAGAGLPGL-----------QRP-LSYKDLEAALAKVGPRASAKELDSFVEWDK 761

  Fly   518 IYGVRH 523
            :||..|
Human   762 MYGSGH 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	51/135 (38%)
		AAA	286..416	CDD:278434	47/129 (36%)
		Vps4_C	<480..520	CDD:286426	8/39 (21%)
FIGNL2	XP_016874787.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23074
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940