DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fign and Nvl

DIOPT Version :9

Sequence 1:	NP_001259995.1	Gene:	Fign / 33544	FlyBaseID:	FBgn0031519	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_001099450.1	Gene:	Nvl / 289323	RGDID:	1311270	Length:	855	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	96/277 - (34%)
Similarity:	154/277 - (55%)	Gaps:	14/277 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 VAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGV-RCPPRGVLLFGPPGTGKTLIAKSIASQAKAK 310
            |.|.|:..||..:.....||:.|:|.|:.|..: ...|.||||.||||.||||:||::|:::...
  Rat   577 VTWADVGALEDIREELTMAILAPVRNPEQFRALGLVAPAGVLLAGPPGCGKTLLAKAVANESGLN 641

  Fly   311 FFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEFLI 375
            |.|:....|.:.:||::|:.|:.:|..|....|.:||.||||:|..:||..|..:::|:.|:.|.
  Rat   642 FISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRETGASVRVVNQLLT 706

  Fly   376 HLDGAASNEEIRVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTREARQKIIEKLI-HQVKHNL 437
            .:||..:.::  |.::.|||||..:|.|:.|  |..:.|:|.||....|..|::.:. :..|..|
  Rat   707 EMDGLETRQQ--VFILAATNRPDIIDPAILRPGRLDKTLFVGLPPPADRVAILKTITKNGTKPPL 769

  Fly   438 DVRQVIELAELT-----DGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQAL 497
            |  :.::|..:.     |.|:|||:..|.|.||:..||.....|...|.|.:| .|:...|::|.
  Rat   770 D--EDVDLEAIANDHRCDCYTGADLSALVREASLCALRQEITGQKNGIGTAEL-TVSHKHFEEAF 831

  Fly   498 RVISKSVSSEDCKQFEA 514
            |.:..|:|.:|.:.:||
  Rat   832 RKVKPSISVKDQRMYEA 848

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	54/137 (39%)
		AAA	286..416	CDD:278434	51/131 (39%)
		Vps4_C	<480..520	CDD:286426	12/35 (34%)
Nvl	NP_001099450.1	Nucleolin_bd	2..71	CDD:406995
Nvl	NP_001099450.1	CDC48	<255..855	CDD:273521	96/277 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810