Protein Alignment Fign and Katnal1

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_705800.1
• Gene: Katnal1 / 231912
• MGIID: 2387638
• Length: 488
• Species: Mus musculus
• Alignment Length: 536
• Identity: 159/536 - (29%)
• Similarity: 279/536 - (52%)
• Gaps: 85/536 - (15%)

  Fly    15 ICQQTRSSSESIHFAALKDHHARL-----------QACESME----KAMKERCQKKITMSRRTKR 64
            ||:..:...|   :|.|.::.:.:           :.|:|:.    ||..::.::::.......:
Mouse     6 ICENAKKGRE---YALLGNYDSSMVYYQGVIQQIQRHCQSLRDPATKAKWQQVRQELLEEYEQVK 67

  Fly    65 GITHAGYLFEMPHNSVFEPECRGFYESCQQTEMASSDLQAPALEVSSTYPVQQAVKSRPEGQFPE 129
            .|......|:|.....|...||            ....:.||:...   ||....::.|:.:.|.
Mouse    68 SIVSTLESFKMDKPPDFPVSCR------------DEPFRDPAVWPP---PVPAEHRAPPQIRRPN 117

  Fly   130 SRNNSTKKIDAQQYSSESSSQSGFGFR--TAREQLIMDELKKKNRQATSEVDAVPTGMMNFRKKT 192
            ......:|            ..|.|.|  ..|..    ::.|.::.|:.:.|        :|.:.
Mouse   118 REVRPLRK------------DVGAGARGLVGRAH----QISKSDKPASRDKD--------YRARG 158

  Fly   193 LGGKRTVSSNFVSPVAQNDNSTSSRSSSIPP-ALAHLDSKMVDHILGESMHDFKPVAWEDIAGLE 256
            ...|           |:.:....:..|.||. ..|..|..:|:.:..:.:.....:.|:|||.||
Mouse   159 RDDK-----------ARKNVQDGASDSEIPKFDGAGYDKDLVEALERDIVSRNPSIHWDDIADLE 212

  Fly   257 SAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTS 321
            .||....||:::|:..||.|.|:|.|.:|||:.||||||||::||::|::....||:::.|:|||
Mouse   213 EAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTS 277

  Fly   322 KWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKR-SANENESTLRLKNEFLIHLD---GAAS 382
            |:.|::||||:.||.:|..:.|..|||||:||:.|:| :::|:|::.|:|:|.||.:|   ||..
Mouse   278 KYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALE 342

  Fly   383 NEE--IRVLVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIEL 445
            |::  ..|:|:.|||.|.::|||:|||..:|:|:||||.:.|.::::..:.:|:.:.|| .:.::
Mouse   343 NDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKISLREVELDPDV-HLEDI 406

  Fly   446 AELTDGYSGADVDTLCRYASMAPLR----SLTPDQMEVI--ETHQLPAVTMDDFKQALRVISKSV 504
            |:.|:||||||:..:||.||:..:|    .|:|:::..:  |..|:| ||..|.:.||:.|:|||
Mouse   407 ADKTEGYSGADITNICRDASLMAMRRRINGLSPEEIRALSKEELQMP-VTRGDLELALKKIAKSV 470

  Fly   505 SSEDCKQFEAWNEIYG 520
            |:.|.:::|.|...:|
Mouse   471 SAADLEKYEKWMVEFG 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	9/49 (18%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	82/190 (43%)
		AAA_lid_3	444..495	CDD:465537	21/56 (38%)
		Vps4_C	<480..520	CDD:462762	16/41 (39%)
Katnal1	NP_705800.1	Kp60-NTD	4..72	CDD:439297	10/68 (15%)
		SpoVK	52..452	CDD:440232	134/450 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..179		20/121 (17%)
		RecA-like_KTNA1	207..376	CDD:410930	79/168 (47%)
		Vps4_C	<448..486	CDD:462762	16/38 (42%)