Protein Alignment Fign and ZK938.3

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001364588.1
• Gene: ZK938.3 / 191468
• WormBaseID: WBGene00014160
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 487
• Identity: 99/487 - (20%)
• Similarity: 166/487 - (34%)
• Gaps: 149/487 - (30%)

  Fly     6 SSWRSKLLLICQQTRSSSESIHFAALKDHHARLQ---ACESMEKAMKERCQKKITMSRRTKRGIT 67
            |:||    :|.|           ||:..|...|:   ||:. :||.:|...|..|.
 Worm   152 STWR----MISQ-----------AAIGHHEHHLEVKRACQE-QKAFRESFLKTQTD--------- 191

  Fly    68 HAGYLFEMPHNSVFEPECRGFYESCQQTEMASSDLQAPALEVSSTYPVQQAVKSRPEGQFPESR- 131
                 |::...:.         |:.|:|::.|  ::...|.:.......||:..|...:|...|
 Worm   192 -----FDIDFENA---------EAEQETQLLS--IEYAVLIIQKLERKYQAISRRNYVRFVRERA 240

  Fly   132 ---NNSTKKIDAQQYSSESSSQS-GFGFRTAREQLIMDELKKKNRQATSEVDAVPTGMMNFRKKT 192
               :....:|||.|.:....::: |:..|....::...||...|....|.:..........||:.
 Worm   241 AELHGLKVEIDATQAAIRIQARTRGYFARKLVREMREKELNILNMTPESYIRKRCAERERKRKEG 305

  Fly   193 LGGKRTVSSNFVSPVAQNDNSTSSRSSSIPPALAHLDSKMVDHILGESMHDFKPVAWEDIAGLES 257
            |.|  .|....:  :.|.:...:..:.::.....|......|      :.|.||.|..  ..|.:
 Worm   306 LAG--GVGGGEI--IEQIEEFNTDLAEALKLLKTHFFFPTSD------LTDIKPSALP--IDLNN 358

  Fly   258 AKSTFLEA----IIMPLRRPDL--FTGVR----------------------CPP----------- 283
            .::.|.:|    |:.||.:.:|  .|..|                      |.|
 Worm   359 QETIFRDACFRGIVSPLAQIELSELTSQREICKIENRQFKFDFRSFLVQTVCTPCSLGTWQKQKS 423

  Fly   284 -----RGVLLFGPPGTGKTL---------------IAKSIASQAKAKFFSINPSSLTSKWVGDAE 328
                 :.:||.|.|.:|||.               |:|::.:..|.|.:::
 Worm   424 KDQKMQWLLLSGAPDSGKTTWARAISRACHVTHVHISKNVVNMGKRKIYTV-------------- 474

  Fly   329 KLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLR--LKNEFLIHLDGAASNEEIRVLVI 391
              ||.|   |...:..::.||.:|  :.|:.......|.|  |...||..|    ||.:. |:||
 Worm   475 --VKKL---AKQEKRLLVSIDRID--VMKKDPKHKGYTHRQILLRNFLSDL----SNIKF-VMVI 527

  Fly   392 GATNRP-QELDEAVRRRFVRRLYVPLPTREAR 422
            |.|..| .:||..:...|..:..:..||...|
 Worm   528 GMTRVPLDDLDSYISDLFPLQATLSNPTNATR 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	13/46 (28%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	52/246 (21%)
		AAA_lid_3	444..495	CDD:465537
		Vps4_C	<480..520	CDD:462762
ZK938.3	NP_001364588.1	IQCD	<253..278	CDD:467745	3/24 (13%)
		AAA	431..545	CDD:459627	35/139 (25%)