Protein Alignment Fign and mac-1

DIOPT Version :9

• Sequence 1: NP_001259995.1
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_496814.1
• Gene: mac-1 / 174974
• WormBaseID: WBGene00003119
• Length: 813
• Species: Caenorhabditis elegans
• Alignment Length: 428
• Identity: 125/428 - (29%)
• Similarity: 205/428 - (47%)
• Gaps: 66/428 - (15%)

  Fly   146 ESSSQSGFGFRTAREQLIMDELKKKNRQ---ATSEVDAVPTGMMNFRKKTL---GGKRTVSSNFV 204
            |:....|....||||: |::::.|.|..   ...::..:..|.:....:.|   ..|..:...|.
 Worm   394 ENEISLGIPDETAREK-ILEKICKVNLAGDVTLKQIAKLTPGYVGADLQALIREAAKVAIDRVFD 457

  Fly   205 SPVAQNDNSTSSRSSSI----------------PPALAHLDSKMVDHILGESMHDFK-------- 245
            :.|.:|:...:.....|                |.||:.|:..     |..|..||:
 Worm   458 TIVVKNEGHKNLTVEQIKEELDRVLAWLQGDDDPSALSELNGG-----LQISFEDFERALSTIQP 517

  Fly   246 -----------PVAWEDIAGLESAKSTFLEAIIMPLRRPDLFT--GVRCPPRGVLLFGPPGTGKT 297
                       .|:|:||..|...:.....:|:.|::|.|.|.  |:.|.|:|:||.||||.|||
 Worm   518 AAKREGFATVPDVSWDDIGALVEVRKQLEWSILYPIKRADDFAALGIDCRPQGILLCGPPGCGKT 582

  Fly   298 LIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANE 362
            |:||::|::....|.|:....|.:.:||::|:.|:|:|..|...||.:||.||:|:|:.|||..|
 Worm   583 LLAKAVANETGMNFISVKGPELLNMYVGESERAVRTVFQRARDSQPCVIFFDEIDALVPKRSHGE 647

  Fly   363 NESTLRLKNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTREARQKI 425
            :....||.|:.|..:||....:  :|.:|||||||..:|.|:.|  |..:.|:|..|:.|.|..|
 Worm   648 SSGGARLVNQLLTEMDGVEGRQ--KVFLIGATNRPDIVDAAILRPGRLDKILFVDFPSVEDRVDI 710

  Fly   426 IEKLIH-----QVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETHQ- 484
            :.|...     .:..::|..::.:|.||. |::|||:..|...:|:..|      |..|:|..:
 Worm   711 LRKSTKNGTRPMLGEDIDFHEIAQLPELA-GFTGADLAALIHESSLLAL------QARVLENDES 768

  Fly   485 LPAVTMDDFKQALRVISKSVSSEDCKQFEAWNEIYGVR 522
            :..|.|..|::|...|..||:..|.|::|...:|||::
 Worm   769 VKGVGMRHFREAASRIRPSVTEADRKKYEHMKKIYGLK 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	57/137 (42%)
		AAA	286..416	CDD:278434	55/131 (42%)
		Vps4_C	<480..520	CDD:286426	12/40 (30%)
mac-1	NP_496814.1	Nucleolin_bd	5..65	CDD:318849
		TIP49	<191..804	CDD:332389	123/424 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810