Protein Alignment Fign and cdc-48.1

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_496273.1
• Gene: cdc-48.1 / 174624
• WormBaseID: WBGene00007352
• Length: 809
• Species: Caenorhabditis elegans
• Alignment Length: 512
• Identity: 126/512 - (24%)
• Similarity: 220/512 - (42%)
• Gaps: 113/512 - (22%)

  Fly    82 EPECRGFYESCQQTEMA-----SSDLQAPALE----------VSSTYPVQQAVKSRPE------- 124
            |...|..:|.|::.:.|     ..|..||..|          ||....:...||.|..
 Worm   289 ESNLRKAFEECEKNQPAILFIDEIDAIAPKREKTNGEVERRIVSQLLTLMDGVKGRSNLVVIAAT 353

  Fly   125 -------------GQF--------PESRNN------STKK------IDAQQYSSESSSQSGFGFR 156
                         |:|        |::...      .||.      :|.:|.::|.....|....
 Worm   354 NRPNSIDGALRRFGRFDREIDIGIPDAVGRLEILRIHTKNMKLADDVDLEQIANECHGFVGADLA 418

  Fly   157 TAREQLIMDELKKKNRQATSEVDAVPTGMMNFRKKTLGGKRTVSSNFVSPVAQNDNSTSSRSSSI 221
            :...:..:.::::|......|.|.:...::|....|:                 :|...::..|.
 Worm   419 SLCSEAALQQIREKMELIDLEDDQIDAEVLNSLAVTM-----------------ENFRFAQGKSS 466

  Fly   222 PPALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKSTFLEAIIMPLRRPDLFT--GVRCPPR 284
            |.||.            |::.:.....|.||.||::.|....|.:..|:..|:.:.  |:: |.|
 Worm   467 PSALR------------EAVVETPNTTWSDIGGLQNVKRELQELVQYPVEHPEKYLKFGMQ-PSR 518

  Fly   285 GVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFID 349
            |||.:||||.||||:||:||::.:|.|.||....|.:.|.|::|..|:.:|..|.|..|.::|.|
 Worm   519 GVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDVFDKARAAAPCVLFFD 583

  Fly   350 EVDSLLSKR----SANENESTLRLKNEFLIHLDGAASNEEIRVLVIGATNRPQELDEAVRR--RF 408
            |:||:...|    ..:...::.|:.|:.|..:||  .|.:..|.:|||||||..:|.||.|  |.
 Worm   584 ELDSIAKARGGGAGGDGGGASDRVINQVLTEMDG--MNAKKNVFIIGATNRPDIIDPAVLRPGRL 646

  Fly   409 VRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSLT 473
            .:.:|:|||...:|.:|::..:.:...:.|: .:..||:.|.|:||||:..:|:.|....:|...
 Worm   647 DQLIYIPLPDEASRHQILKASLRKTPLSKDL-DLTFLAKNTVGFSGADLTEICQRACKLAIRESI 710

  Fly   474 PDQMEVIETHQ-----------------LPAVTMDDFKQALRVISKSVSSEDCKQFE 513
            ..::.:.:..|                 :|.:|...|::|::...:||:..|.:::|
 Worm   711 EKEIRIEKERQDRQARGEELMEDDAVDPVPEITRAHFEEAMKFARRSVTDNDIRKYE 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	66/192 (34%)
		AAA_lid_3	444..495	CDD:465537	15/67 (22%)
		Vps4_C	<480..520	CDD:462762	9/51 (18%)
cdc-48.1	NP_496273.1	CDC48	52..775	CDD:273521	126/512 (25%)