Protein Alignment Fign and Pex1

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_061513544.1
• Gene: Pex1 / 1271027
• VectorBaseID: AGAMI1_013104
• Length: 1141
• Species: Anopheles gambiae
• Alignment Length: 278
• Identity: 87/278 - (31%)
• Similarity: 136/278 - (48%)
• Gaps: 26/278 - (9%)

  Fly   247 VAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPR---GVLLFGPPGTGKTLIAKSIASQAK 308
            |..:.:.|||.|...|.|.::.|.|.|.:|..  .|.|   |:|||||||||||.:...:|....
Mosquito   853 VPGDKVPGLEGAIEVFQEVLMWPTRFPKIFEA--SPLRNQAGILLFGPPGTGKTYLVSKLAKTWN 915

  Fly   309 AKFFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEF 373
            .:..|:....|.:|::|.:|:.|:.||..|.:.:|.::|.||.|||..:|..:....|.|:.|:.
Mosquito   916 LRMISVKGPELLAKYIGQSEENVRNLFDRARSAKPCVLFFDEFDSLAPRRGHDSTGVTDRVVNQL 980

  Fly   374 LIHLDGAASNEEIRVLVIGATNRPQELDEAVRR--RFVRRLYVPLPTREARQKIIEKLIHQVKHN 436
            |..|||....:  .|.|||||:||:.||.|:.|  |..|.:...||...||.:|.......:..:
Mosquito   981 LTELDGVEGLQ--GVTVIGATSRPELLDPALLRSGRIDRLVECTLPGVTARLEIFSNHSKSLTLD 1043

  Fly   437 LDVRQVIELAELTDGYSGADVDTLCRYASMAPLRSL-------TPDQMEVIETHQLPAVTMDDFK 494
            .|| .:.|.|..::.|:|||:.::...|:|..::..       .|:|:.|.:.|         ..
Mosquito  1044 KDV-DLREFAVKSEYYTGADIRSILTTANMLAVQECLSNDPEKVPEQITVSQRH---------LA 1098

  Fly   495 QALRVISKSVSSEDCKQF 512
            :|......|:|..|..::
Mosquito  1099 EAFSSTRPSLSPRDIAKY 1116

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	64/171 (37%)
		AAA_lid_3	444..495	CDD:465537	12/57 (21%)
		Vps4_C	<480..520	CDD:462762	5/33 (15%)
Pex1	XP_061513544.1	None