DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fign and fign

DIOPT Version :9

Sequence 1:	NP_001259995.1	Gene:	Fign / 33544	FlyBaseID:	FBgn0031519	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_004917757.1	Gene:	fign / 100488151	XenbaseID:	XB-GENE-1011106	Length:	783	Species:	Xenopus tropicalis

Alignment Length:	454	Identity:	147/454 - (32%)
Similarity:	238/454 - (52%)	Gaps:	54/454 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 LFEMPHNSVFEP-ECRGFYESCQQTEMASSDLQAPALEVSSTYPVQQAVKSRPEGQFPESRNNST 135
            ::.||.:|:... ...||..|.:...:|..             |.:|.|.|..:.:|   .|.||
Frog   376 MYRMPDSSITNSNRGNGFDRSAETGSLAFK-------------PTKQLVPSDQQRKF---NNQST 424

  Fly   136 KKIDAQQYSSESSSQSGFGFRTAREQLIMDELKKKNRQATSEVD----AVPTGMMNFRKKTLGGK 196
            :.:....|||..:|:|.            |...|.|..|.:|..    .:|..|..      .|.
Frog   425 RALTPPSYSSTKNSRSS------------DSFGKYNSSALNEHSDEHRLIPHTMQG------PGL 471

  Fly   197 RTVSSNFVSPVAQNDNSTSSRSSSIPPALAHLDSKMVDHILGESMHDFKPVAWEDIAGLESAKST 261
            .|.:|:               :.|:...|.:.||.::|.:..|.::...||.|::||||:..|:.
Frog   472 HTATSS---------------NHSVDDQLKNTDSHLIDLVTNEIINQGHPVDWDEIAGLDLVKAF 521

  Fly   262 FLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAKFFSINPSSLTSKWVGD 326
            ..|.::.|:.|.|.|:|:...||.:|||||.||||||:.:.||||..|.||.|:.|:|.:||:.:
Frog   522 IKEEVLWPVIRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKISASNLVTKWITE 586

  Fly   327 AEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRSANENESTLRLKNEFLIHLDGAASNEEIRVLVI 391
            .||:|...|.||...||::||:.::|.|||.:...|:....|::.|||:.||...|:.|.:::||
Frog   587 GEKIVHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPISRMRTEFLMQLDTVLSSAEDQIVVI 651

  Fly   392 GATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLIHQVKHNLDVRQVIELAELTDGYSGAD 456
            .||::|:::||::||.|::||.:|||...||.:||.:|:.|..:.|:.::|..|.:.|:|:||.|
Frog   652 CATSKPEQIDESLRRYFMKRLLIPLPDSTARHQIIIQLLSQHNYCLNDKEVALLVQRTEGFSGLD 716

  Fly   457 VDTLCRYASMAPLRSLTPDQMEVIETHQLPAVTMDDFKQALRVISKSVSSEDCKQFEAWNEIYG 520
            |..||:.|.:.||.::.|..:..|..:||..||..||:.....|..|:|.::...:..||:::|
Frog   717 VARLCQEAVVGPLHAIPPSDLSAIMPNQLRPVTYQDFENVFCKIQPSISQKELDTYIEWNKMFG 780

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_001259995.1	AAA	282..418	CDD:214640	62/135 (46%)
		AAA	286..416	CDD:278434	58/129 (45%)
		Vps4_C	<480..520	CDD:286426	12/39 (31%)
fign	XP_004917757.1	SpoVK	<507..770	CDD:223540	107/262 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	335	1.000	Inparanoid score	I2360
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176820at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48355
Panther	1	1.100	-	-	O	PTHR23074
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1766
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.070