Protein Alignment Fign and katnal2

DIOPT Version :10

• Sequence 1: NP_608763.2
• Gene: Fign / 33544
• FlyBaseID: FBgn0031519
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001090643.1
• Gene: katnal2 / 100036615
• XenbaseID: XB-GENE-5827282
• Length: 542
• Species: Xenopus tropicalis
• Alignment Length: 550
• Identity: 166/550 - (30%)
• Similarity: 288/550 - (52%)
• Gaps: 92/550 - (16%)

  Fly    42 ESMEKAMKERCQKKI-TMSRRTKRGITHAGYLFEMPHNSVFEPECRGFYESC----QQTEMA--- 98
            :::..|.:.|..::: |.:||....|....||.:           .|:.:|.    |:|:::
 Frog     6 QALRVASQNREAEELRTEARRKNLLILIMHYLLQ-----------EGYMDSANSLEQETKISLRR 59

  Fly    99 -----SSDLQAPALEVSSTYPVQ---------------QAVKSRPE--GQFPESRNNSTKKID-- 139
                 :.||:...:|..|.|.::               ..|:|:|.  |:...:.:|||:.:.
 Frog    60 FDVCDNVDLETILMEYESYYYIKFQKYPKITKKALDHDSRVQSKPRSAGKLRRAGSNSTQGLPRI 124

  Fly   140 AQQYSSESSSQSGFGFRT-AREQLIMDELKKKNRQATSEVDAVPTGM-MNFRKKTLG-GKRTVSS 201
            ||| :......||..||| |.::.:..|..|:.....|..:|...|: ::...||.| |.:|...
 Frog   125 AQQ-TVLHRPVSGSYFRTHAHQKALSRENSKQENGGNSPREASEIGLNVSAISKTSGEGGQTRRR 188

  Fly   202 NFV--------------SPVAQNDNSTSSRSSS--IPPALAHL--DSKM--VDHILGESMHDFKP 246
            ..:              ..:|.|..:.:...|.  |.|..|.:  :|:|  :..::...::...|
 Frog   189 QVIDFRSMIQDTIKGASQEIALNSLNCNPDPSERLIKPVGAFIGGNSEMRELAAVISRDIYLQNP 253

  Fly   247 -VAWEDIAGLESAKSTFLEAIIMPLRRPDLFTGVRCPPRGVLLFGPPGTGKTLIAKSIASQAKAK 310
             |.|:||.||::||....||::.|:|.|.||||:..|.:|:||:|||||||||:||::|::....
 Frog   254 NVRWDDIIGLDAAKRLVKEAVVYPIRYPQLFTGILSPWKGLLLYGPPGTGKTLLAKAVATECNTT 318

  Fly   311 FFSINPSSLTSKWVGDAEKLVKTLFAVAAAHQPAIIFIDEVDSLLSKRS---ANENESTLRLKNE 372
            ||:|:.|::.|||.||:||||:.||.:|..|.|:.||:||::|::|:|.   ..|:|.:.|:|.|
 Frog   319 FFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGTGPGGEHEGSRRMKTE 383

  Fly   373 FLIHLDGAASNEEIRVLVIGATNRPQELDEAVRRRFVRRLYVPLPTREARQKIIEKLIHQVKHN- 436
            .|:.:||.|.:::: |.|:.|:|.|.|||.|:.||..:|:.|.||::||||.:|:..:..|.::
 Frog   384 LLVQMDGLARSDDL-VFVLAASNLPWELDYAMLRRLEKRILVDLPSKEARQAMIQHWLPPVSNSS 447

  Fly   437 -LDVRQVIELAEL---TDGYSGADVDTLCRYASMAPLRSLTPDQMEVIETH-----QLPAVTMD- 491
             :::|..::.:.|   ||||||:|:..:|:.|:|.|:|.:    .:.:|.|     .||.:::|
 Frog   448 GVELRTDLDYSTLGAETDGYSGSDIRLVCKEAAMRPVRKI----FDALENHHSEHKNLPVISLDT 508

  Fly   492 ----DFKQALRVISKSVSSEDCKQFEAWNE 517
                ||.:.|.....|..|. .:::.||.:
 Frog   509 VTTSDFLEVLAHTKPSAKSL-AEKYAAWQK 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fign	NP_608763.2	PH-like	<4..50	CDD:473070	1/7 (14%)
		P-loop containing Nucleoside Triphosphate Hydrolases	229..414	CDD:476819	82/190 (43%)
		AAA_lid_3	444..495	CDD:465537	20/63 (32%)
		Vps4_C	<480..520	CDD:462762	12/47 (26%)
katnal2	NP_001090643.1	LisH	25..57	CDD:128913	9/42 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..126		7/31 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..168		5/25 (20%)
		RPT1	197..526	CDD:440835	120/333 (36%)