Protein Alignment CG3277 and fgfr1b

DIOPT Version :9

• Sequence 1: NP_608762.3
• Gene: CG3277 / 33543
• FlyBaseID: FBgn0031518
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001155204.1
• Gene: fgfr1b / 567905
• ZFINID: ZDB-GENE-060503-14
• Length: 740
• Species: Danio rerio
• Alignment Length: 826
• Identity: 202/826 - (24%)
• Similarity: 327/826 - (39%)
• Gaps: 244/826 - (29%)

  Fly    12 VLILLLVLVRNAVGQAPRENATNPTLIS---LVRSSEKE-------------------------- 47
            :|:|||:|.:....|      :.|.:..   :|.|||.|
Zfish    18 LLVLLLILTQLCTVQ------SRPAVTEQGHIVASSEDEDDDESSSEENKPSSSQELLPMAPRWA 76

  Fly    48 -PEQMESHRYVTGLSEPIAMEPLTRMRLNPNPDGEITELTTNVTLYMEKIPRLQVRWQDNLPQGT 111
             ||:||...:....|:.:..    |.:...||                 ||:|  ||   |..|.
Zfish    77 QPEKMEKKLHAVPASKTVKF----RCQAEGNP-----------------IPKL--RW---LKNGK 115

  Fly   112 SYNVLVSAVNNSRCPDAPCSEYGIKEKNASAETHSVNLPVNPNLNVESVDCNYMFGCQYQVIVET 176
            .:.           .|.....|.::|...:....||         |.|...||.  |    :||.
Zfish   116 EFK-----------RDQRIGGYKLREHMWTIIMESV---------VPSDKGNYT--C----LVEN 154

  Fly   177 SNAMVRRSARVYIPQCLEGKCSCQLAPTPPKVLAVAKMLSNETISINLSILASELLRKEQDSHLH 241
            ....:..:.::.:           :..:|.:.:..|.:.:|.|     :::.|::
Zfish   155 EYGSINHTYQLDV-----------VERSPHRPILYAGLPANRT-----AVVGSDV---------- 193

  Fly   242 ETLRTYKMQLKINEETNPSLPWGGVLKHLMTRVYKLSELNFRATPKGFEGVMKL---GLGTQLKE 303
                  :...|:..:..|.:.|   |||:.....:|.       |.|...|..|   ||.|..||
Zfish   194 ------EFVCKVFSDPQPHIQW---LKHIRVNGSQLG-------PDGLPYVRVLKTAGLNTTDKE 242

  Fly   304 KASLSLQAVIIDPTG---CEGPRSV---------TKVPVPANPVLLTEGDSVSNSIIVMSAMLIA 356
            ...|.|:.|..:..|   |....|:         |.|..|..|..: ...|....:|......:.
Zfish   243 MEVLQLRNVSFEDAGEYTCLAGNSIGISHHSAWLTVVKAPTAPSAV-PSQSYLEVLIYCIGFFLI 306

  Fly   357 IILAGLIMLLLRRRRAR--------TTAKLRKQEQIYIQTFATSAIEMEDNVNYVDKYVEKSQ-- 411
            .::.|:..::..|..::        ...||.|  .|.::...|.::|...::|.....|..|:
Zfish   307 FLMVGIATIVKIRSSSKKSDFNSQLAVHKLAK--SIPLRRQITVSVESSSSLNSGVMLVRPSRLS 369

  Fly   412 ------VLGLAD-------IFEVPHSAIQIGRMLGEGAFGQVHEATAINLRRMRGTTI--VAVKQ 461
                  :.|:::       .:||....:.:|:.||||.||||....||.|.:.:...|  ||||.
Zfish   370 SSGTPMLSGVSEYELPQDPCWEVSRERLVLGKPLGEGCFGQVVMGEAIGLDKDKPNRITKVAVKM 434

  Fly   462 LKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVRKEA 526
            ||.:....::::.::|:||:|.:|.|.|:::.||.||...|..:|:|:.:||||..|||..|
Zfish   435 LKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARR--- 496

  Fly   527 SKLRNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFA 591
                                     |......|                         .|.|...
Zfish   497 -------------------------PHGMEYCY-------------------------NPDPLPI 511

  Fly   592 ETTYTIVEDEDAFEYILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFG 656
            |:              :..|:|.:.|.|:|.||.:|..::..||||||||||:..:..:||:|||
Zfish   512 ES--------------MSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFG 562

  Fly   657 LSR--HGI--YTNTRTRKLPLRWLSIEAIRENVYSSKSDIWAYGVVLWEIGTLGASPYPTISNDE 717
            |:|  |.|  |..|...:||::|::.||:.:.:|:.:||:|::||:||||.|||.||||.:..:|
Zfish   563 LARDVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEE 627

  Fly   718 LIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVL 763
            |...|..|:|:::|..||.::|.:|..||...|.:||||..|.:.|
Zfish   628 LFKLLREGHRMDKPSACTQELYLMMKDCWHAVPTQRPTFKQLVEDL 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3277	NP_608762.3	STYKc	426..763	CDD:214568	115/342 (34%)
		PTKc	430..763	CDD:270623	114/338 (34%)
fgfr1b	NP_001155204.1	I-set	80..167	CDD:254352	25/138 (18%)
		Ig2_FGFR	83..167	CDD:143265	23/135 (17%)
		IG_like	182..278	CDD:214653	25/126 (20%)
		Ig3_FGFR-2	190..278	CDD:143266	23/113 (20%)
		PKc_like	383..684	CDD:304357	118/358 (33%)
		Pkinase_Tyr	397..673	CDD:285015	115/342 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810