DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3277 and Styk1

DIOPT Version :9

Sequence 1:	NP_608762.3	Gene:	CG3277 / 33543	FlyBaseID:	FBgn0031518	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	XP_038964794.1	Gene:	Styk1 / 500340	RGDID:	1564211	Length:	436	Species:	Rattus norvegicus

Alignment Length:	483	Identity:	119/483 - (24%)
Similarity:	208/483 - (43%)	Gaps:	136/483 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 IIVMSAMLIA---IILAGLIMLLLRRRRAR--------TT----AKLRKQ------EQIYIQTFA 390
            :|::.|:|:.   |:||.::.|.:|.:|::        ||    ::.|.|      |::::....
  Rat    37 VIIVPALLVGSFLILLAIILWLFIRGQRSQRQHPGPRGTTSVPASRGRSQEAVGHGEKVFVPLKE 101

  Fly   391 TSAIEMEDNVNYVDKYVEKSQV--LGLADIFEVPHSAIQIGRMLGEGAFGQVHEATAINLRRMRG 453
            ||   :|..:..|...:.|.||  ..|.::.|..||          |:.|.::.|....:.....
  Rat   102 TS---VESFLRAVTPSLAKLQVPREQLLEVLEQIHS----------GSCGTLYHAKMTTMEHPNP 153

  Fly   454 TTIVAVKQLKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSY 518
            .::| :|.|:.:....||.:::..|:..:.:|.|.|:|...||||.:.|..|::|.|..|:||::
  Rat   154 KSVV-LKALEGSVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTERLPLYMMLEDVVPGDLLNF 217

  Fly   519 LRTVRKEASKLRNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGI 583
            |.|.|                |.:||                                   |:|:
  Rat   218 LWTCR----------------RDVMT-----------------------------------MDGL 231

  Fly   584 RQPHPSFAETTYTIVEDEDAFEYILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNK 648
            .                     |.|..|::::...|:...:.||:|:.:.|.|:||||:||.|:.
  Rat   232 L---------------------YDLTEKQIYHIGKQVLLALEFLQEKHLFHGDVAARNILIQSDL 275

  Fly   649 TLKISDFGLS----RHGIYTNTRTRKLPLRWLSIEAIRENVYSSKSDIWAYGVVLWEIGTLGASP 709
            |.|:...||:    .||..::.|:..:||:||:.|.:.....|.:.|:|::|::|:|:.||||.|
  Rat   276 TPKLCHLGLAYEVHTHGAISSARSSTIPLKWLAPERLLLRPASIRGDVWSFGILLYEMVTLGAPP 340

  Fly   710 YPTISNDELIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPEERP-------TFDALYKVLSPKT 767
            ||.:....::.:|.....::||..||..:|.||..||....:.||       ..:|..:..:.|.
  Rat   341 YPEVPPTSILQYLQRKKIMKRPSSCTHAMYNIMKYCWRWSEDSRPLPGELRLRLEAASRTANDKA 405

  Fly   768 T-----------YVDI-----NSLSDDY 779
            .           |.|:     .||||.|
  Rat   406 VLQVPELVVPDLYADVAGISTESLSDSY 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3277	NP_608762.3	STYKc	426..763	CDD:214568	86/347 (25%)
CG3277	NP_608762.3	PTKc	430..763	CDD:270623	86/343 (25%)
Styk1	XP_038964794.1	PKc_like	130..395	CDD:419665	88/347 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900