DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3277 and fgfrl1a

DIOPT Version :9

Sequence 1:	NP_608762.3	Gene:	CG3277 / 33543	FlyBaseID:	FBgn0031518	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	NP_956670.1	Gene:	fgfrl1a / 393347	ZFINID:	ZDB-GENE-040128-2	Length:	483	Species:	Danio rerio

Alignment Length:	466	Identity:	83/466 - (17%)
Similarity:	150/466 - (32%)	Gaps:	182/466 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 VYIPQCLEGKCSCQLAPTPPKVLAVAKMLSNETISINLSILASELLRKEQDSHLHETLRTYKMQL 251
            ::|..|..|         ||:|  ..|:...:|:.|.                     ||.|:|.
Zfish    14 IFITDCARG---------PPRV--AEKIAHRQTVRIG---------------------RTMKLQC 46

  Fly   252 KINEETNPSLPW---------GGVLKHLMTRVYKLSELN--------FRATPKGFEGVMKLGLGT 299
            .:..:..|.:.|         |.:...::.:..::.|:.        .:|| .||..|
Zfish    47 PVEGDPPPLIMWTKDGRNIHSGWMRFRVLQQALRIKEVEADDAGTFICKAT-NGFGSV------- 103

  Fly   300 QLKEKASLSLQAVIIDPT--GCEGPRSVTKVPVPANPVLLTEGDSVSNSIIVMSAMLIAIILAGL 362
                  :::...::||.:  |.||.|       ||..   ||               .:..|.|.
Zfish   104 ------NINYTLIVIDDSSAGREGAR-------PAGE---TE---------------YSTDLTGK 137

  Fly   363 IMLLLRRRRARTTAKLRKQEQIYIQTFATSAIEMEDNVNYVDKYVEKSQVLGLADIFEVPHSAIQ 427
            ::    |.|....||:||:   .|.....|::.::...:...:          .||..:..|...
Zfish   138 LV----RPRFTQPAKMRKR---VIARPVGSSVRLKCTASGNPR----------PDIVWLKDSRPL 185

  Fly   428 IGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKP----------NPKADEV-AEYLAEIEML 481
            ....:|||             |:.:.|  :::|.|.|          :.:|.|: |.|..|:...
Zfish   186 TPEEVGEG-------------RKKKWT--LSLKNLTPEHSGKYTCHVSNRAGEINATYKVEVIQR 235

  Fly   482 KG-----VGTH--HNVVSFLGC----CTIK---PPYLMIMEYVNKGNLLSYLRTV---------- 522
            ..     .|||  :..|.:.|.    |.::   .|.:..::.|..|....|..|:
Zfish   236 TNSKPILTGTHPVNTTVDYGGTTSFQCKVRSDVKPVIQWLKRVEPGGEGKYNSTIEVGDHHFVVL 300

  Fly   523 -------RKEASKLRNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHM 580
                   |.:.|.|.         :.::||     :.:..:..||.|.|::    |.....:|.:
Zfish   301 PTGDVWSRPDGSYLN---------KLLITR-----AKEEDAGMYICLGANT----MGYSFRSAFL 347

  Fly   581 NGIRQPHPSFA 591
            ..:..|.|.|:
Zfish   348 TVLPDPKPPFS 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3277	NP_608762.3	STYKc	426..763	CDD:214568	38/208 (18%)
CG3277	NP_608762.3	PTKc	430..763	CDD:270623	38/204 (19%)
fgfrl1a	NP_956670.1	I-set	32..111	CDD:254352	15/113 (13%)
		IGc2	38..101	CDD:197706	12/84 (14%)
		I-set	141..232	CDD:254352	22/118 (19%)
		Ig2_FGFRL1-like	151..232	CDD:143264	18/108 (17%)
		I-set	245..349	CDD:254352	21/121 (17%)
		Ig	255..350	CDD:299845	18/112 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900