DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3277 and Fgfrl1

DIOPT Version :9

Sequence 1:	NP_608762.3	Gene:	CG3277 / 33543	FlyBaseID:	FBgn0031518	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	NP_954545.1	Gene:	Fgfrl1 / 360903	RGDID:	735156	Length:	529	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	42/217 - (19%)
Similarity:	71/217 - (32%)	Gaps:	61/217 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 GKCSCQLAPTPPKVLAVAKMLSNETISINLSILASELLRKEQDSHLHETL---------RTYKMQ 250
            ||.:|:              :||...:||.:.....:.|......|..|.         .|...|
  Rat   213 GKYTCR--------------VSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQ 263

  Fly   251 LKINEETNPSLPWGGVLKHLMTRVYKLSELNFRAT-PKGFEGVMKLGLGTQLKEKASLSLQAVII 314
            .|:..:..|.:.|       :.||...||....:| ..|.:..:.|..|..........|..::|
  Rat   264 CKVRSDVKPVIQW-------LKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLI 321

  Fly   315 -----DPTG---CEGPRS---------VTKVPVPANPVLLTEGDSVSNSI--------IVMSAML 354
                 |..|   |.|..:         :|.:|.|..|     |..|::|.        :|:....
  Rat   322 SRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPP-----GPPVAHSSSTTSLPWPVVIGIPA 381

  Fly   355 IAIILAGLIMLLLRRRRARTTA 376
            .|:.:.|.::|.|.:.:.:..|
  Rat   382 GAVFILGTVLLWLCQTKKKPCA 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3277	NP_608762.3	STYKc	426..763	CDD:214568
CG3277	NP_608762.3	PTKc	430..763	CDD:270623
Fgfrl1	NP_954545.1	I-set	29..112	CDD:400151
		Ig strand A'	35..38	CDD:409353
		Ig strand B	41..50	CDD:409353
		Ig strand C	56..61	CDD:409353
		Ig strand C'	64..67	CDD:409353
		Ig strand D	72..77	CDD:409353
		Ig strand E	78..84	CDD:409353
		Ig strand F	91..99	CDD:409353
		Ig strand G	102..112	CDD:409353
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	117..152
		IgI_2_FGFRL1-like	143..234	CDD:409442	7/34 (21%)
		Ig strand B	164..168	CDD:409442
		Ig strand C	177..181	CDD:409442
		Ig strand E	200..204	CDD:409442
		Ig strand F	214..219	CDD:409442	2/18 (11%)
		Ig strand G	227..230	CDD:409442	1/2 (50%)
		Ig	242..350	CDD:416386	21/114 (18%)
		Ig strand A	242..245	CDD:409353	0/2 (0%)
		Ig strand A'	249..253	CDD:409353	0/3 (0%)
		Ig strand B	261..268	CDD:409353	2/6 (33%)
		Ig strand C	272..279	CDD:409353	2/13 (15%)
		Ig strand D	304..309	CDD:409353	1/4 (25%)
		Ig strand E	317..322	CDD:409353	0/4 (0%)
		Ig strand F	330..338	CDD:409353	3/7 (43%)
		Ig strand G	341..349	CDD:409353	0/7 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	405..427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900